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Decoding a ribosome uncertainty
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DOI：10.1016/j.tig.2023.06.001.png)
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The ribosome is among the most ancient macromolecular complexes. Throughout evolution, the function of the ribosome has remained essential and conserved: the decoding of an mRNA template with tRNA-linked amino acids, to synthesize a protein. In a recent study, Holm et al. capture evolutionary distinctions in the structure and kinetics of 'mRNA decoding' by the human ribosome.
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TRANSFER-RNA
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