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EMBO Journal 封面图

EMBO Journal

IF8.3
论文数13151
被引数63397
期刊论文 13151
发表时间
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A unified mechanism for mitochondrial damage sensing in PINK1-Parkin–mediated mitophagyPINK1-Parkin-mediated线粒体噬细胞线粒体损伤感知的统一机制
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IF8.3
delete2025-11-20
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deleteJulia A Thayer; Jennifer D Petersen; Xiaoping Huang; Luiza M Gruel Budet; James Hawrot; Daniel M Ramos; Shiori Sekine; Yan Li; Michael E Ward; Derek P Narendra
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C-reactive protein is a broad-spectrum capsule-binding receptor for hepatic capture of blood-borne bacteriaC-reactive protein是肝细胞捕获血液中细菌的广谱胶囊结合受体。
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IF8.3
delete2025-11-10
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deleteDanyu Chen; Jiao Hu; Mengran Zhu; Yufeng Xie; Hantian Yao; Haoran An; Yumin Meng; Juanjuan Wang; Xueting Huang; Yanni Liu; Zhujun Shao; Ye Xiang; Jianxun Qi; George Fu Gao; Jing-Ren Zhang
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Distinct senotypes in p16- and p21-positive cells across human and mouse aging tissues人和小鼠衰老组织中p16-和p21阳性细胞中独特的表型。
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IF8.3
delete2025-10-29
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deleteDominik Saul; Diana Jurk; Madison L Doolittle; Robyn Laura Kosinsky; Yeaeun Han; Xu Zhang; Ana Catarina Franco; Sung Y Kim; Saranya P Wyles; Y S Prakash; David G Monroe; Luigi Ferrucci; Nathan K LeBrasseur; Paul D Robbins; Laura J Niedernhofer; Sundeep Khosla; João F Passos
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A widely-occurring family of pore-forming effectors broadens the impact of the Serratia Type VI secretion systemReglinski, M.; Hurst, Q.W.; Williams, D.J.; Gierlinski, M.; Şahin, A.T.; Mathers, K.; Ostrowski, A.; Bergkessel, M.; Zachariae, U.; Pitt, S.J.; 等. 一种广泛存在的成孔效应蛋白家族扩大了erratia型六分泌系统的影晌。Embo J. 2025; 提前在线发表。 [Google Scholar] [CrossRef] [PubMed]
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IF8.3
delete2025-10-21
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deleteMark Reglinski; Quenton W Hurst; David J Williams; Marek Gierlinski; Alp Tegin Şahin; Katharine Mathers; Adam Ostrowski; Megan Bergkessel; Ulrich Zachariae; Samantha J Pitt; Sarah J Coulthurst
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RNF114 and RNF166 exemplify reader-writer E3 ligases that extend K11 polyubiquitin onto sites of MARUbylationRNF114和RNF166是典型的读写器E3泛素连接酶，它们在MARUbylation位点延伸K11多泛素化修饰。
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IF8.3
delete2025-10-02
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deleteRachel E Lacoursiere; Kapil Upadhyaya; Jasleen Kaur Sidhu; Ivan Rodriguez Siordia; Daniel S Bejan; Michael S Cohen; Jonathan N Pruneda
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MCM5 UFMylation regulates replication origin firing and fork progressionMCM5泛素样修饰调控复制起点激活和复制叉进程
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IF8.3
delete2025-09-12
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deleteZheng Li; Xingxuan Wu; Liu Liu; Shaohong Rao; Yanting Liao; Mengting Liu; Bin Peng; Qiongdan Zhang; Yisui Xia; Yuanliang Zhai; Shunichi Takeda; Xingzhi Xu
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Shigella type-III secretion system effectors counteract the induction of host inflammation and cell death
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IF8.3
delete2025-09-10
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deleteHiroshi Ashida; Tokuju Okano; Tamako Iida; Poramed Onsoi; Chihiro Sasakawa; Toshihiko Suzuki
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Host cell and viral protease targets of human SERPINs identified by in silico dockingRodriguez Galvan, J.; de Vries, M.; Belblidia, S.; Fisher, A.; Prescott, R.A.; Crosse, K.M.; Hearing, P.; Mangel, W.F.; Duerr, R.; Dittmann, M. 人源SERPINs识别宿主细胞和病毒蛋白酶靶点的方法：基于计算机对接技术。EMBO J. 2025, 44, 5755–5784. [Google Scholar] [CrossRef] [PubMed]
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IF8.3
delete2025-09-08
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deleteJoaquin Rodriguez Galvan; Maren de Vries; Shiraz Belblidia; Ashley Fisher; Rachel A Prescott; Keaton M Crosse; Patrick Hearing; Walter F Mangel; Ralf Duerr; Meike Dittmann
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Basal IFN-λ2/3 expression mediates tight junction formation in human epithelial cellsKeser Y，Metz-Zumaran C，Uckeley ZM，Reuss D，Doldan P，Ramsden JM，等. 基础IFN-λ2/3表达介导人类上皮细胞紧密连接的形成。EMBO J. (2025). doi: 10.1038/s44318-025-00539-5
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IF8.3
delete2025-09-01
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deleteYagmur Keser; Camila Metz-Zumaran; Zina M Uckeley; Dorothee Reuss; Patricio Doldan; James M Ramsden; Megan L Stanifer; Steeve Boulant
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deleteEMBO Journal
IF8.3
delete2025-08-18
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deleteDongteng Liu; Yuxiang Zhang; Dongliang Li; Binjie Jiang; Xudong Zhao; Yanyan Li; Zexiong Lin; Yu Zhao; Zhe Hu; Shuzi Deng; Zheng Li; Haonan Lu; Karen K L Chan; William S B Yeung; Philipp Kaldis; Chencheng Yao; Hengbin Wang; Louise T Chow; Kui Liu
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Tau uptake by human neurons depends on receptor LRP1 and kinase LRRK2tau的摄取依赖于人类神经元中的受体LRP1和激酶LRRK2
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IF8.3
delete2025-08-11
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deleteLewis D Evans; Alessio Strano; Eleanor Tuck; Ashley Campbell; James Smith; Christy Hung; Tiana S Behr; Bernardino Ghetti; Benjamin Ryskeldi-Falcon; Emre Karakoc; Francesco Iorio; Alastair Reith; Andrew R Bassett; Frederick J Livesey
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mTORC1 senses glutamine and other amino acids through GCN2mTORC1通过GCN2感知谷氨酰胺和其他氨基酸
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IF8.3
delete2025-07-21
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deleteGianluca Figlia; Sandra Müller; Fabiola Garcia-Cortizo; Marilena Neff; Glynis Klinke; Gernot Poschet; Aurelio A Teleman
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Human fetal kidney organoids model early human nephrogenesis and Notch-driven cell fate
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IF8.3
delete2025-07-21
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deleteMichael Namestnikov; Osnat Cohen-Zontag; Dorit Omer; Yehudit Gnatek; Sanja Goldberg; Thomas Vincent; Swati Singh; Yair Shiber; Tal Rafaeli Yehudai; Hadas Volkov; Dani Folkman Genet; Achia Urbach; Sylvie Polak-Charcon; Igor Grinberg; Naomi Pode-Shakked; Boaz Weisz; Zvi Vaknin; Benjamin S Freedman; Benjamin Dekel
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Amyloid-β disrupts APP-regulated protein aggregation and dissociation from recycling endosomal membranesAβ破坏APP调控的蛋白质聚集和从再循环内体膜的解离
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IF8.3
delete2025-07-17
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deletePreman J Singh; Bhavna Verma; Adam Wells; Cláudia C Mendes; Dali Dunn; Ying-Ni Chen; Jade Oh; Lewis Blincowe; S Mark Wainwright; Roman Fischer; Shih-Jung Fan; Adrian L Harris; Deborah C I Goberdhan; Clive Wilson
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Proteomic aging signatures across mouse organs and life stages
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IF8.3
delete2025-07-15
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deleteEnzo Scifo; Sarah Morsy; Ting Liu; Kan Xie; Kristina Schaaf; Daniele Bano; Dan Ehninger
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TERRA R-loops trigger a switch in telomere maintenance towards break-induced replication and PRIMPOL-dependent repairIn, S.; Renck Nunes, P.; Valador Fernandes, R.; Lingner, J. TERRA R-loop触发了向断裂诱导复制和PrimPol依赖性修复的端粒维持转变。bioRxiv 2025. [Google Scholar] [CrossRef] [PubMed]
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IF8.3
delete2025-07-07
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deleteSuna In; Patricia Renck Nunes; Rita Valador Fernandes; Joachim Lingner
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A chromatin-remodeling-independent role for ATRX in protecting centromeric cohesionATRX在保护着丝粒连接中的染色质重塑非依赖性作用
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IF8.3
delete2025-05-28
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deleteZhao, Lei; Yuan, Xueying; Chen, Qinfu; Yan, Haiyan; Wang, Fangwei
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Super-resolution imaging of native fluorescent photoreceptors in chytrid fungal eyes蛙壶菌真菌眼天然荧光感光器的超分辨率成像
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IF8.3
delete2025-05-27
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deleteBusse, Wayne; Klotzsch, Enrico; Kamrani, Yousef Yari; Wordtmann, Natalie; Kelterborn, Simon; Hegemann, Peter; Broser, Matthias
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Landscape of the Epstein-Barr virus-host chromatin interactome and gene regulationEpstein-Barr病毒-宿主染色质互作组景观与基因调控
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IF8.3
delete2025-05-27
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deleteTian, Simon Zhongyuan; Yang, Yang; Ning, Duo; Yu, Ting; Gao, Tong; Deng, Yuqing; Fang, Ke; Xu, Yewen; Jing, Kai; Huang, Guangyu; Chen, Gengzhan; Yin, Pengfei; Li, Yiming; Zeng, Fuxing; Tian, Ruilin; Zheng, Meizhen
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Parthenolide disrupts mitosis by inhibiting ZNF207/BUGZ-promoted kinetochore-microtubule attachmentParthenolide通过抑制ZNF207/BUGZ促进的动粒-微管连接来干扰有丝分裂。
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IF8.3
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deleteEibes, Susana; Lakshmi, R. Bhagya; Rajendraprasad, Girish; Weinert, Brian T.; Kamounah, Fadhil S.; Gamon, Luke F.; Rodriguez-Calado, Sergi; Meldal, Morten; Davies, Michael J.; Pittelkow, Michael; Choudhary, Chunaram; Barisic, Marin
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