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Deep Learning for Antimicrobial Peptides: Computational Models and Databases

delete2025-02-10
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PRE
AI
X
Xiangrun Zhou
G
Guixia Liu *
S
Shuyuan Cao
J
Ji Lv *
DOI:10.1021/acs.jcim.5c00006delete
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摘要

摘要

En 中文
Antimicrobial peptides are a promising strategy to combat antimicrobial resistance. However, the experimental discovery of antimicrobial peptides is both time-consuming and laborious. In recent years, the development of computational technologies (especially deep learning) has provided new opportunities for antimicrobial peptide prediction. Various computational models have been proposed to predict antimicrobial peptide. In this review, we focus on deep learning models for antimicrobial peptide prediction. We first collected and summarized available data resources for antimicrobial peptides. Subsequently, we summarized existing deep learning models for antimicrobial peptides and discussed their limitations and challenges. This study aims to help computational biologists design better deep learning models for antimicrobial peptide prediction.
Keyword:
antimicrobial peptides
antimicrobial resistance
deep learning
databases

期刊

Journal of Chemical Information and Modeling 封面图
Journal of Chemical Information and Modeling
IF:
5.3
论文数:
9.1K
被引数:
4.0W

机构

Z
Zhejiang Normal University
学者数:
1.3W
论文数: 8.4K
被引数: 1.2W
J
Jilin University
学者数:
8.7W
论文数: 5.6W
被引数: 8.9K
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