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Degradation of Ethyl Carbamate by Lichtheimia ramosa EC-2 from Baijiu Daqu: Optimization, Metabolites, and Key Enzymes
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DOI：10.1016/j.fm.2026.105206.png)
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Abstract
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• Lichtheimia ramosa EC-2 degraded ethyl carbamate by 42.29% within 7 days. • Strain EC-2 tolerated high ethyl carbamate levels and up to 15% (v/v) ethanol. • Multi-omics suggested a shift of carbon flux toward acetyl-CoA-related metabolism during EC utilization. • EC-2 altered community functions related to carbon/nitrogen metabolism and reduced arginine-related precursor pathways. • A novel amidase (TR3551) hydrolyzed EC and remained active under elevated temperature and ethanol.
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