DNA-PAINT adaptors make for efficient multiplexing

Matthew D. Lycas

doi:10.1016/j.crmeth.2024.100801

2024-06-01

Matthew D. Lycas

Suliana Manley *

DOI：10.1016/j.crmeth.2024.100801

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摘要

En 中文

Multiplexed super -resolution imaging offers a route to spatial proteomics; however, time -efficient mapping of many protein species has been challenging. Two recent works in Cell highlight SUM -PAINT and FLASHPAINT, methods that leverage adaptor DNA strand design to combine advances in multiplexing with increases in speed of label exchange. These advances permit unbiased omics-style analyses to advance biological insights from super -resolution images.

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期刊

Cell Reports Methods

IF:

4.5

论文数:

945

被引数:

2.0K

机构

swiss federal institutes of technology domain

学者数:

9.0W

论文数: 8.0W

被引数: 163

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