Dyslexia (specific reading disability)

doi:10.1016/j.biopsych.2005.01.043

2005-06-01

746

Sally E. Shaywitz

Bennett A. Shaywitz

DOI：10.1016/j.biopsych.2005.01.043

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摘要

En 中文

Converging evidence from a number of lines of investigation indicates that dyslexia represents a disorder within the language system and more specifically within a particular subcomponent of that system, phonological processing. Recent advances in imaging technology. particularly the development of functional magnetic resonance imaging, provide evidence of a, neurobiological signature for dyslaxia, specifically a disruption of two left hemisphere posterior brain systems, one parieto-lemporal, the other occipito-temporal, with compensatory engagement of anterior systems around the inferior frontal gyrus and a posterior (right occipito-temporal) system. Furthermore, good evidence indicates a computational role for the left occipito-temporal system the development of fluent (automatic) reading. The brain systems for reading are malleable and their disruption in dyslexic children may be remediated by provision of an evidence-based. effective reading intervention. In addition, functional magnetic resonance imaging studies of young adults with, reading difficulties and longitudinally from age 5 through their mid twenties suggests that their may be two types of reading difficulties, one primarily on a genetic basis, the other, and far more common, reflecting environmental influences. These studies offer the promise for more precise identification and effective management of dyslexia in children, adolescents and adults.

Keyword:

reading

dyslexia

brain imaging

functional magnetic resonance imaging (fMRI)