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Endocannabinoids

delete1998-10-01
delete478
PRE
AI
R
Raphael Mechoulam
E
Ester Fride
D
Di Marzo, V
DOI：10.1016/S0014-2999(98)00649-9delete
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摘要

摘要

En 中文
The background knowledge leading to the isolation and identification of anandamide and 2-arachidanoyl glycerol, the principal endocannabinoids is described. The structure-activity relationships of these lipid derivatives are summarized. Selected biochemical and pharmacological topics in this field are discussed, the main ones being levels of endocannabinoids in unstimulated tissue and cells, biosynthesis, release and inactivation of endocannabinoids, the effects of 'entourage' compounds on the activities of anandamide and 2-arachidonoyl glycerol, their signaling mechanisms and effects in animals. (C) 1998 Elsevier Science B.V. All rights reserved.
Keyword:
anandamide
2-arachidonoyl glycerol
tetrahydrocannabinol
cannabis
AI总结

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对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。

期刊

European Journal of Pharmacology 封面图
European Journal of Pharmacology
IF:
4.7
论文数:
2.3W
被引数:
4.0W

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