logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
返回期刊详情
Life Sciences 封面图

Life Sciences

IF5.1
论文数17883
被引数46566
期刊论文 17883
发表时间
delete
SphK1/S1P signaling network: From molecular mechanism to therapeutic targetingSphK1/S1P信号网络：从分子机制到治疗靶向
deleteLife Sciences
IF5.1
delete2026-10-27
delete0
PREAI
deleteDuxiao Yang; Zhen Wang
delete分享
delete收藏
OGT-mediated O-GlcNAcylation stabilizes EGR1 to drive vascular leakage in acute respiratory distress syndromeOGT介导的O-GlcNAc糖基化稳定EGR1以驱动急性呼吸窘迫综合征中的血管渗漏
deleteLife Sciences
IF5.1
delete2026-10-27
delete0
PREAI
deleteFan Li; Wenqing Yan; Wenqiang Zhou; Zhi Chen
delete分享
delete收藏
Genetic GHSR deficiency and LEAP2 treatment enhance the glucose-lowering effects of liraglutide in male mice in a metabolic state-dependent manner遗传性GHSR缺陷和LEAP2处理以代谢状态依赖性方式增强雄性小鼠中利拉鲁肽的降血糖效果
deleteLife Sciences
IF5.1
delete2026-10-26
delete0
deleteOAAI
deleteDaniela A. Cassano; Gimena Fernandez; María P. Cornejo; Sepideh Sheybani-Deloui; Julieta Aguggia; Sonia Cantel; Jean-Alain Fehrentz; Abdella M. Habib; Laura Rolland; Magalie A. Ravier; María F. Andreoli; Jeffrey M. Zigman; Helgi B. Schiöth; Mario Perello
delete分享
delete收藏
Overcoming the efficacy–safety dilemma of cytokine therapy for tissue-resident memory T cells in cancer immunotherapy: Intrinsic sensitization and extrinsic optimization克服癌症免疫疗法中针对组织驻留记忆T细胞的细胞因子治疗的有效性-安全性困境：内在致敏和外在优化
deleteLife Sciences
IF5.1
delete2026-10-24
delete0
PREAI
deleteYao Xiao; Zi-Zhan Li; Zhi-Jun Sun
delete分享
delete收藏
Immunometabolic checkpoint: The dual regulatory role of macrophages in islet destruction in type 1 diabetes免疫代谢检查点：巨噬细胞在1型糖尿病胰岛破坏中的双重调控作用
deleteLife Sciences
IF5.1
delete2026-10-24
delete0
PREAI
deleteJin Deng; Jianliang Lu; Wei Wang; Qingyang Liu
delete分享
delete收藏
Early PEG-bHb resuscitation for hemorrhagic shock: Attenuation of acute kidney injury via the Nrf2/HO-1 pathway早期PEG-bHb复苏治疗失血性休克：通过Nrf2/HO-1通路减轻急性肾损伤
deleteLife Sciences
IF5.1
delete2026-10-24
delete0
PREAI
deleteHang Yu; Guoxing You; Yuzhi Chen; Weidan Li; Xiaoyong Zhang; Hong Zhou; Lian Zhao; Ying Wang
delete分享
delete收藏
Bergenin attenuates diabetic cardiomyopathy by inhibiting oxidative stress and ferroptosis through modulation of the YAP signaling axisbergenin通过调节YAP信号轴抑制氧化应激和铁死亡来减轻糖尿病心肌病
deleteLife Sciences
IF5.1
delete2026-10-24
delete0
PREAI
deleteSourav Kundu; Manisha Yadav; Madhav Nilakanth Mugale; Bidya Dhar Sahu
delete分享
delete收藏
One protein, many faces: TRAF1 from signaling hub to disease diversity一个蛋白质，多种功能：从信号中心到疾病多样性的TRAF1
deleteLife Sciences
IF5.1
delete2026-10-20
delete0
PREAI
deleteYu-hang Liu; Run-shi Xu; Jin-qiang Hu; Xin Tong; Cong-cong He; Xing-Hua Gao
delete分享
delete收藏
Minimal essentials for humanized vessel-on-a-chip model for vascular research血管研究用人源化血管芯片模型的最小必要条件
deleteLife Sciences
IF5.1
delete2026-10-19
delete0
deleteOAAI
deleteAmparo Romero-Picó; Laura Vázquez-Vázquez; Diana Rodríguez-Suárez; Simón Rodríguez-Moar; Bruno K. Rodiño-Janeiro; Carmen Bao-Varela; Sonia Eiras; José R. González-Juanatey; Rosa M. Agra-Bermejo; Ezequiel Álvarez
delete分享
delete收藏
Role and mechanism of ATF6-mediated endoplasmic reticulum stress in ITLN-1 against cerebral ischemia-reperfusion injuryATF6介导的内质网应激在ITLN-1抵抗脑缺血再灌注损伤中的作用及机制
deleteLife Sciences
IF5.1
delete2026-10-19
delete0
PREAI
deleteYanqing Liu; Lu Xu; Zhe Zhang; Caiqin Zhang; Peijie Liu; Pan Li; Shuya Wang; Ye Tian; Yang Yang; Xiaochen Niu
delete分享
delete收藏
Dapagliflozin alleviates CYH33-induced hyperglycemia and preserves antitumor immunity against ovarian cancer in type 1 diabetic mice达格列净减轻CYH33诱导的高血糖并维持1型糖尿病小鼠中对抗卵巢癌的抗肿瘤免疫
deleteLife Sciences
IF5.1
delete2026-10-17
delete0
PREAI
deleteJiaqi Sun; Lan Xu; Hui Qu; Xi Zhang; Xiaoyu Ma; Ying Leng; Linghua Meng
delete分享
delete收藏
Circadian system and human health: From molecular mechanisms to clinical integration昼夜节律系统与人类健康：从分子机制到临床整合
deleteLife Sciences
IF5.1
delete2026-10-16
delete0
PREAI
deleteTao Fan; Xing Wei; Ping Lin; Yinggao Liu; Yuan Tian
delete分享
delete收藏
ELF1 exacerbates intervertebral disc degeneration by promoting ACSL4-dependent ferro-aging of nucleus pulposus cells through the IFITM3-PTPRO axisELF1通过IFITM3-PTPRO轴促进ACSL4依赖性铁老化加剧髓核细胞退行性变
deleteLife Sciences
IF5.1
delete2026-10-15
delete0
PREAI
deleteJia-Hao Lu; Shan-Shan Huang; Hao-Wei Xu; Shu-Bao Zhang; Sheng-Jie Chang; Fei-Yang Wu; Xiao-Wei Liu; Shan-Jin Wang
delete分享
delete收藏
Porphyromonas gingivalis lipopolysaccharide induces osteoblast senescence and defective mineralization associated with indoleamine 2,3-dioxygenase 1–kynurenine–aryl hydrocarbon receptor signalingPorphyromonas gingivalis脂多糖通过色氨酸2,3-双加氧酶1-犬尿氨酸-芳烃受体信号通路诱导成骨细胞衰老和矿化缺陷
deleteLife Sciences
IF5.1
delete2026-10-14
delete0
PREAI
deleteShuguang Han; Wenlong Zhang; Xiaoli Zhang; Mingyong Wang; Yu Jiang
delete分享
delete收藏
Orai3 deficiency drives atrial remodeling and fibrillation susceptibility via Orai channel remodeling and SOCE hyperactivationOrai3缺乏通过Orai通道重塑和SOCE过度激活驱动心房重构和颤动易感性
deleteLife Sciences
IF5.1
delete2026-10-13
delete0
PREAI
deleteXiaohe Wu; Yangcheng Xue; Haoyang Lu; Yanlong Cao; Danni Li; Ao Liang; Peiyang Zheng; Ran Zhang; Zhuoran Jia; Ren Zhao
delete分享
delete收藏
β-Hydroxybutyrate alleviates intestinal aGVHD via remodeling gut microbiota-bile acid axis and inhibiting TLR4-NF-κB-driven Th1/Th17 differentiationβ-羟基丁酸通过重塑肠道微生物-胆汁酸轴并抑制TLR4-NF-κB驱动的Th1/Th17分化来缓解肠道aGVHD
deleteLife Sciences
IF5.1
delete2026-10-13
delete0
PREAI
deleteRuixue Tian; Chao Deng; Kexin Liu; Hurong Lai; Caifeng Liao; Huaijun Tu; Jian Li
delete分享
delete收藏
Inhibition of the MEK-ERK signaling pathway reverses acquired osimertinib resistance in NSCLC attributed to AXL overexpressionMEK-ERK信号通路的抑制逆转了由AXL过表达引起的非小细胞肺癌获得性奥希替尼耐药
deleteLife Sciences
IF5.1
delete2026-10-13
delete0
deleteOAAI
deleteKai Zhang; Xiying Yu; Yue Liu; Huan Zhang; Xin Wang; Peng Jiang; Xiaomi Li; Yang Su; Yuan Gao; Hongqian Chu; Tongmei Zhang; Hongxia Li
delete分享
delete收藏
UDP-glucose ceramide glucosyltransferase (UGCG) is a novel positive regulator of MyD88-driven inflammation in sepsisUDP-葡萄糖神经酰胺葡萄糖基转移酶（UGCG）是脓毒症中MyD88驱动的炎症反应的新型正向调控因子
deleteLife Sciences
IF5.1
delete2026-10-12
delete0
PREAI
deleteYidi Ding; Xuan Zhong; Fangfang Li; Lina Yan; Wen Tian; Xiaofei Yang; Huanjun Shen; Xuyang Zheng; Jianqi Lian
delete分享
delete收藏
Molecular stratification of ovarian insufficiency via novel MicroRNA signatures and target gene suppression通过新型microRNA特征和靶基因抑制对卵巢功能不全进行分子分层
deleteLife Sciences
IF5.1
delete2026-10-09
delete0
PREAI
deleteParsa Tafazoli; Hanieh Motahari Rad; Fatemeh Siadat; Mehri Mashayekhi; Sharif Moradi; Rouhollah Fathi
delete分享
delete收藏
Combined erythropoietin and sodium butyrate ameliorate imiquimod-induced lupus-like autoimmunity in mice through modulation of inflammatory and interferon-associated responses联合促红细胞生成素和丁酸钠通过调节炎症和干扰素相关反应改善咪喹莫特诱导的小鼠狼疮样自身免疫
deleteLife Sciences
IF5.1
delete2026-10-07
delete0
PREAI
deleteQamar Othman; Waleed Barakat El-Bahouty; Samia H. Abou El-Seoud; Nehal K.H. Kamel; Mahmoud F.A. Fayez
delete分享
delete收藏