.png){kind=icon}
返回
EST2Prot: Mapping EST sequences to proteins
.png){kind=icon}
OA
AI
DOI：10.1186/1471-2164-7-41.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Background: EST libraries are used in various biological studies, from microarray experiments to proteomic and genetic screens. These libraries usually contain many uncharacterized ESTs that are typically ignored since they cannot be mapped to known genes. Consequently, new discoveries are possibly overlooked. Results: We describe a system ( EST2Prot) that uses multiple elements to map EST sequences to their corresponding protein products. EST2Prot uses UniGene clusters, substring analysis, information about protein coding regions in existing DNA sequences and protein database searches to detect protein products related to a query EST sequence. Gene Ontology terms, SwissProt keywords, and protein similarity data are used to map the ESTs to functional descriptors. Conclusion: EST2Prot extends and significantly enriches the popular UniGene mapping by utilizing multiple relations between known biological entities. It produces a mapping between ESTs and proteins in real-time through a simple web- interface. The system is part of the Biozon database and is accessible at http://biozon.org/tools/est/.
Keyword:
ABC TRANSPORTER SUPERFAMILY
GENE PREDICTION
DATABASE
TOOL
UNIFICATION
MANAGEMENT
ALIGNMENT
PROGRAM
MEMBER
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
3.7
论文数:
1.9W
被引数:
5.2W
机构
暂无机构信息
引用论文
The TIGR Gene Indices: analysis of gene transcript sequences in highly sampled eukaryotic species.png)
NUCLEIC ACIDS RESEARCH
OAAI
NUCLEIC ACIDS RESEARCHIF13.1
OAAI分享收藏MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancerMOLECULAR MEDICINEOAAI
MOLECULAR MEDICINEIF6.4
OAAI分享收藏Comparative Metabolomic Analysis of an Alternative Biosynthetic Pathway to Pseudosugars in Actinosynnema mirum DSM 43827ChemBioChemOAAI
ChemBioChemIF0
OAAI分享收藏
查看更多内容