Humanizing pig kidneys via chimeric complementation

Jia Huang

doi:10.1038/s41422-023-00881-5

2023-10-13

Jia Huang

Jun Wu *

DOI：10.1038/s41422-023-00881-5

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摘要

En 中文

An ultimate goal in stem cell research is to use induced pluripotent stem cells (iPSCs) to generate transplant able human organs in large livestock. In a groundbreaking study by Wang et al., the researchers showcased that by combining an optimized iPSC culture, tactics to boost the survival and competitive edge of donor human cells, and a genetically vacated host organ niche, they could successfully produce a humanized mesonephros within pig fetuses, a significant leap in the field

Keyword:

CELLS

期刊

Cell Research

IF:

25.9

论文数:

3.8K

被引数:

2.9W

机构

university of texas system

学者数:

18.5W

论文数: 15.6W

被引数: 210

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