Inflaming the Brain

doi:10.1016/j.neuron.2019.03.007

2019-03-01

DOI：10.1016/j.neuron.2019.03.007

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Exactly how cerebrovascular alterations contribute to Alzheimer's disease (AD) is still unknown. Merlini et al. (2019) show that blood-derived fibrinogen leads to dendritic spine elimination and cognitive deficit via microglial CD11b/CD18. Fibrinogen may be a significant contributor to AD pathogenesis.

Keyword:

ALZHEIMERS-DISEASE

FIBRINOGEN

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Neuron

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1.4W

被引数:

9.9W

机构

rutgers university system

学者数:

4.1W

论文数: 3.7W

被引数: 53

rutgers university biomedical & health sciences

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6.3K

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被引数: 7

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