InterPro in 2022

doi:10.1093/nar/gkac993

2022-11-09

1.1K

Typhaine Paysan‐Lafosse *

Arun Prasad Pandurangan

Catherine Rivoire

Christian J A Sigrist

DOI：10.1093/nar/gkac993

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摘要

En 中文

The InterPro database (https://www.ebi.ac.uk/interpro/) provides an integrative classification of protein sequences into families, and identifies functionally important domains and conserved sites. Here, we report recent developments with InterPro (version 90.0) and its associated software, including updates to data content and to the website. These developments extend and enrich the information provided by InterPro, and provide a more user friendly access to the data. Additionally, we have worked on adding Pfam website features to the InterPro website, as the Pfam website will be retired in late 2022. We also show that InterPro's sequence coverage has kept pace with the growth of UniProtKB. Moreover, we report the development of a card game as a method of engaging the non-scientific community. Finally, we discuss the benefits and challenges brought by the use of artificial intelligence for protein structure prediction.

Keyword:

FAMILY CLASSIFICATION

PROTEIN STRUCTURES

DATABASE

PREDICTION

TOPOLOGY

AI总结

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期刊

Nucleic Acids Research

IF:

13.1

论文数:

3.6W

被引数:

29.0W

机构

national institutes of health (nih) - usa

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university of geneva

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Georgetown University

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Google Incorporated

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被引数: 8

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