Lucy J. Colwell - Publications, H-index & Citations

Lucy J. Colwell

google research

36H指数

90论文数

9.8K被引数

收录论文 32

发表时间

Does sequence clustering confound AlphaFold2?序列聚类是否会影响AlphaFold2？

Journal of Molecular Biology

IF4.5

2025-08-06

OAAI

Hannah K. Wayment-Steele; Sergey Ovchinnikov; Lucy Colwell; Dorothee Kern

Engineering highly active nuclease enzymes with machine learning and high-throughput screening 利用机器学习和高通量筛选工程化高活性核酸酶

CELL SYSTEMS

IF7.7

2025-03-01

OAAI

Thomas, Neil; Belanger, David; Xu, Chenling; Lee, Hanson; Hirano, Kathleen; Iwai, Kosuke; Polic, Vanja; Nyberg, Kendra D.; Hoff, Kevin G.; Frenz, Lucas; Emrich, Charlie A.; Kim, Jun W.; Chavarha, Mariya; Ramanan, Abi; Agresti, Jeremy J.; Colwell, Lucy J.

The Pfam protein families database: embracing AI/ML

NUCLEIC ACIDS RESEARCH

IF13.1

2024-11-14

OAAI

Paysan-Lafosse, Typhaine; Andreeva, Antonina; Blum, Matthias; Chuguransky, Sara Rocio; Grego, Tiago; Pinto, Beatriz Lazaro; Salazar, Gustavo A.; Bileschi, Maxwell L.; Llinares-Lopez, Felipe; Meng-Papaxanthos, Laetitia; Colwell, Lucy J.; Grishin, Nick, V; Schaeffer, R. Dustin; Clementel, Damiano; Tosatto, Silvio C. E.; Sonhammer, Erik; Wood, Valerie; Bateman, Alex

Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency

NATURE CHEMISTRY

IF20.2

2024-05-16

OAAI

Puszkarska, Anna M.; Taddese, Bruck; Revell, Jefferson; Davies, Graeme; Field, Joss; Hornigold, David C.; Buchanan, Andrew; Vaughan, Tristan J.; Colwell, Lucy J.

ProteInfer, deep neural networks for protein functional inference 蛋白质fer，用于蛋白质功能推断的深度神经网络

ELIFE

IF0

2023-02-27

OAAI

Sanderson, Theo; Bileschi, Maxwell L.; Belanger, David; Colwell, Lucy J.; Doetsch, Volker

Hallucinating functional protein sequences

NATURE BIOTECHNOLOGY

IF41.7

2023-01-26

PREAI

Belanger, David; Colwell, Lucy J.

MGnify: the microbiome sequence data analysis resource in 2023 MGnify: 微生物组序列数据分析资源2023年

NUCLEIC ACIDS RESEARCH

IF13.1

2022-12-07

OAAI

Richardson, Lorna; Allen, Ben; Baldi, Germana; Beracochea, Martin; Bileschi, Maxwell L.; Burdett, Tony; Burgin, Josephine; Caballero-Perez, Juan; Cochrane, Guy; Colwell, Lucy J.; Curtis, Tom; Escobar-Zepeda, Alejandra; Gurbich, Tatiana A.; Kale, Varsha; Korobeynikov, Anton; Raj, Shriya; Rogers, Alexander B.; Sakharova, Ekaterina; Sanchez, Santiago; Wilkinson, Darren J.; Finn, Robert D.

InterPro in 2022 InterPro 2022年

NUCLEIC ACIDS RESEARCH

IF13.1

2022-11-09

1.1K

OAAI

Paysan-Lafosse, Typhaine; Blum, Matthias; Chuguransky, Sara; Grego, Tiago; Pinto, Beatriz Lazaro; Salazar, Gustavo A.; Bileschi, Maxwell L.; Bork, Peer; Bridge, Alan; Colwell, Lucy; Gough, Julian; Haft, Daniel H.; Letunic, Ivica; Marchler-Bauer, Aron; Mi, Huaiyu; Natale, Darren A.; Orengo, Christine A.; Pandurangan, Arun P.; Rivoire, Catherine; Sigrist, Christian J. A.; Sillitoe, Ian; Thanki, Narmada; Thomas, Paul D.; Tosatto, Silvio C. E.; Wu, Cathy H.; Bateman, Alex

A roadmap for the functional annotation of protein families: a community perspective

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION

IF3.6

2022-08-12

OAAI

de Crecy-Lagard, Valerie; de Hegedus, Rocio Amorin; Arighi, Cecilia; Babor, Jill; Bateman, Alex; Blaby, Ian; Blaby-Haas, Crysten; Bridge, Alan J.; Burley, Stephen K.; Cleveland, Stacey; Colwell, Lucy J.; Conesa, Ana; Dallago, Christian; Danchin, Antoine; de Waard, Anita; Deutschbauer, Adam; Dias, Raquel; Ding, Yousong; Fang, Gang; Friedberg, Iddo; Gerlt, John; Goldford, Joshua; Gorelik, Mark; Gyori, Benjamin M.; Henry, Christopher; Hutinet, Geoffrey; Jaroch, Marshall; Karp, Peter D.; Kondratova, Liudmyla; Lu, Zhiyong; Marchler-Bauer, Aron; Martin, Maria-Jesus; McWhite, Claire; Moghe, Gaurav D.; Monaghan, Paul; Morgat, Anne; Mungall, Christopher J.; Natale, Darren A.; Nelson, William C.; O'Donoghue, Sean; Orengo, Christine; O'Toole, Katherine H.; Radivojac, Predrag; Reed, Colbie; Roberts, Richard J.; Rodionov, Dmitri; Rodionova, Irina A.; Rudolf, Jeffrey D.; Saleh, Lana; Sheynkman, Gloria; Thibaud-Nissen, Francoise; Thomas, Paul D.; Uetz, Peter; Vallenet, David; Carter, Erica Watson; Weigele, Peter R.; Wood, Valerie; Wood-Charlson, Elisha M.; Xu, Jin

Using sequence data to predict the self-assembly of supramolecular collagen structures

BIOPHYSICAL JOURNAL

IF3.1

2022-08-01

OAAI

Puszkarska, Anna M.; Frenkel, Daan; Colwell, Lucy J.; Duer, Melinda J.

Using deep learning to annotate the protein universe

NATURE BIOTECHNOLOGY

IF41.7

2022-02-21

123

OAAI

Bileschi, Maxwell L.; Belanger, David; Bryant, Drew; Sanderson, Theo; Carter, Brandon; Sculley, D.; Bateman, Alex; DePristo, Mark A.; Colwell, Lucy J.

The effect of chemical representation on active machine learning towards closed-loop optimization

REACTION CHEMISTRY & ENGINEERING

IF3.1

2022-01-01

OAAI

Pomberger, A.; McCarthy, A. A. Pedrina; Khan, A.; Sung, S.; Taylor, C. J.; Gaunt, M. J.; Colwell, L.; Walz, D.; Lapkin, A. A.

Minding the gaps: The importance of navigating holes in protein fitness landscapes

CELL SYSTEMS

IF7.7

2021-11-01

OAAI

Thomas, Neil; Colwell, Lucy J.

Deep diversification of an AAV capsid protein by machine learning

NATURE BIOTECHNOLOGY

IF41.7

2021-02-11

182

PREAI

Bryant, Drew H.; Bashir, Ali; Sinai, Sam; Jain, Nina K.; Ogden, Pierce J.; Riley, Patrick F.; Church, George M.; Colwell, Lucy J.; Kelsic, Eric D.

Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase-tRNA pairs

NATURE BIOTECHNOLOGY

IF41.7

2020-04-13

OAAI

Cervettini, Daniele; Tang, Shan; Fried, Stephen D.; Willis, Julian C. W.; Funke, Louise F. H.; Colwell, Lucy J.; Chin, Jason W.

Glycation changes molecular organization and charge distribution in type I collagen fibrils

SCIENTIFIC REPORTS

IF3.9

2020-02-25

OAAI

Bansode, Sneha; Bashtanova, Uliana; Li, Rui; Clark, Jonathan; Mueller, Karin H.; Puszkarska, Anna; Goldberga, Ieva; Chetwood, Holly H.; Reid, David G.; Colwell, Lucy J.; Skepper, Jeremy N.; Shanahan, Catherine M.; Schitter, Georg; Mesquida, Patrick; Duer, Melinda J.

The Effect of Debiasing Protein-Ligand Binding Data on Generalization

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2019-12-11

PREAI

Sundar, Vikram; Colwell, Lucy

Computational approaches to therapeutic antibody design: established methods and emerging trends

BRIEFINGS IN BIOINFORMATICS

IF7.7

2019-10-18

126

OAAI