.png){kind=icon}
返回
Microfluidic techniques for high throughput single cell analysis
.png){kind=icon}
OA
AI
DOI：10.1016/j.copbio.2016.02.015.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
The microfabrication of microfluidic control systems and the development of increasingly sensitive molecular amplification tools have enabled the miniaturization of single cells analytical platforms. Only recently has the throughput of these platforms increased to a level at which populations can be screened at the single cell level. Techniques based upon both active and passive manipulation are now capable of discriminating between single cell phenotypes for sorting, diagnostic or prognostic applications in a variety of clinical scenarios. The introduction of multiphase microfluidics enables the segmentation of single cells into biochemically discrete picoliter environments. The combination of these techniques are enabling a class of single cell analytical platforms within great potential for data driven biomedicine, genomics and transcriptomics.
Keyword:
CIRCULATING TUMOR-CELLS
LABEL-FREE
INERTIAL MICROFLUIDICS
DROPLET MICROFLUIDICS
NANOLITER DROPLETS
INDIVIDUAL CELLS
CHIP
SEPARATION
PLATFORM
FILTRATION
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
7
论文数:
5.0K
被引数:
1.9W
机构
引用论文
A microfluidic device for label-free, physical capture of circulating tumor cell clusters用于无标记，物理捕获循环肿瘤细胞簇的微流控设备.png)
NATURE METHODSOAAI
NATURE METHODSIF32.1
OAAI分享收藏On-chip single-copy real-time reverse-transcription PCR in isolated picoliter dropletsANALYTICAL CHEMISTRY
OAAI
ANALYTICAL CHEMISTRYIF6.7
OAAI分享收藏A Generalizable, Tunable Microfluidic Platform for Delivering Fast Temporally Varying Chemical Signals to Probe Single-Cell Response DynamicsANALYTICAL CHEMISTRYOAAI
ANALYTICAL CHEMISTRYIF6.7
OAAI分享收藏A Radial Flow Microfluidic Device for Ultra-High-Throughput Affinity-Based Isolation of Circulating Tumor CellsSMALLOAAI
SMALLIF12.1
OAAI分享收藏Cell separation based on size and deformability using microfluidic funnel ratchetsLAB ON A CHIP
LAB ON A CHIPIF5.4
PREAI
分享收藏High-purity and label-free isolation of circulating tumor cells (CTCs) in a microfluidic platform by using optically-induced-dielectrophoretic (ODEP) forceLAB ON A CHIP
LAB ON A CHIPIF5.4
PREAI
分享收藏
查看更多内容