.png){kind=icon}
返回
Neurogenesis-mediated forgetting minimizes proactive interference
.png){kind=icon}
OA
AI
DOI：10.1038/ncomms10838.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Established memories may interfere with the encoding of new memories, particularly when existing and new memories overlap in content. By manipulating levels of hippocampal neurogenesis, here we show that neurogenesis regulates this form of proactive interference. Increasing hippocampal neurogenesis weakens existing memories and, in doing so, facilitates the encoding of new, conflicting (but not non-conflicting) information in mice. Conversely, decreasing neurogenesis stabilizes existing memories, and impedes the encoding of new, conflicting information. These results suggest that reduced proactive interference is an adaptive benefit of neurogenesis-induced forgetting.
Keyword:
ADULT HIPPOCAMPAL NEUROGENESIS
MEMORY
NEURONS
INCREASES
SYSTEMS
BRAIN
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
15.7
论文数:
9.4W
被引数:
91.2W
机构
引用论文
Artificial bee colony algorithm with scanning strategy for the periodic vehicle routing problem基于扫描策略的人工蜂群算法求解周期性车辆路径问题.png)
SIMULATION
SIMULATIONIF0
PREAI
分享收藏WHY THERE ARE COMPLEMENTARY LEARNING-SYSTEMS IN THE HIPPOCAMPUS AND NEOCORTEX - INSIGHTS FROM THE SUCCESSES AND FAILURES OF CONNECTIONIST MODELS OF LEARNING AND MEMORY为什么在海马和新大脑皮层中存在互补的学习系统-来自学习和记忆的连接主义模型的成功和失败的见解PSYCHOLOGICAL REVIEW
PSYCHOLOGICAL REVIEWIF5.8
PREAI
分享收藏
查看更多内容