Noncoding RNA

Emma Desgranges

doi:10.1128/microbiolspec.GPP3-0038-2018

2019-04-12

DOI：10.1128/microbiolspec.GPP3-0038-2018

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摘要

En 中文

Regulatory RNAs, present in many bacterial genomes and particularly in pathogenic bacteria such as Staphylococcus aureus, control the expression of genes encoding virulence factors or metabolic proteins. They are extremely diverse and include noncoding RNAs (sRNA), antisense RNAs, and some 5' or 3' untranslated regions of messenger RNAs that act as sensors for metabolites, tRNAs, or environmental conditions (e.g., temperature, pH). In this review we focus on specific examples of sRNAs of S. aureus that illustrate how numerous sRNAs and associated proteins are embedded in complex networks of regulation. In addition, we discuss the CRISPR-Cas systems defined as an RNA-interference-like mechanism, which also exist in staphylococcal strains.

Keyword:

STAPHYLOCOCCUS-AUREUS REVEALS

TOXIN-ANTITOXIN SYSTEMS

QUORUM SENSING CONTROLS

T-BOX RIBOSWITCH

MESSENGER-RNA

REGULATORY RNA

VIRULENCE

GENES

TRANSCRIPTION

ADAPTATION

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期刊

Microbiology Spectrum

IF:

3.8

论文数:

8.4K

被引数:

3.3W

机构

universites de strasbourg etablissements associes

学者数:

146

论文数: 320

被引数: 6.8K

centre national de la recherche scientifique (cnrs)

学者数:

24.5W

论文数: 18.2W

被引数: 17.4W

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