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PLoS Genetics 封面图

PLoS Genetics

IF3.7
论文数9762
被引数45660
期刊论文 9762
发表时间
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Predicting antifolate resistance in the unculturable fungal pathogen Pneumocystis jirovecii预测不可培养真菌病原体——伊氏肺孢子菌的抗叶酸耐药性
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deleteRouleau, Francois D.; Dube, Alexandre K.; Pageau, Alicia; Desautels, Lyne; Dufresne, Philippe; Landry, Christian R.
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Species-specific coevolution of RecA-RecN interfaces governs DNA double-strand break repair in Escherichia coli物种特异性的RecA-RecN界面共进化调控大肠杆菌中的DNA双链断裂修复
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deleteInoue, Mizuki; Akanuma, Genki; Hayashi, Masafumi; Hishida, Takashi
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Yap1 regulates motility and vertebral development and prevents kyphoscoliosis in zebrafishYap1调控运动能力与脊椎发育并预防斑马鱼脊柱侧后凸
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deleteWilliams-Ward, Victoria C.; Wanders, Kees; Hughes, Simon M.
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FabF and FadM cooperate to recycle fatty acids and rescue △plsX lethality in Staphylococcus aureusFabF和FadM协同作用以回收脂肪酸并拯救金黄色葡萄球菌中△plsX的致死性
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deleteWongdontree, Paprapach; Palmier, Milya; Louche, Clara; Leguillier, Vincent; Rodrigues, Carine Machado; Gloux, Karine; Halpern, David; Henry, Celine; Anba-Mondoloni, Jamila; Gruss, Alexandra
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mFABIO: An integrative multi-tissue TWAS fine-mapping approach to prioritize potentially causal genes and tissues underlying binary traitsmFABIO：一种整合多组织TWAS精细定位方法，用于优先识别二元性状潜在的因果基因和组织
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deleteZhang, Haihan; He, Kevin; Tsoi, Lam C.; Zhou, Xiang
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MR2G: A novel framework for causal network inference using GWAS summary dataMR2G: 一种利用全基因组关联研究汇总数据构建因果网络的全新框架
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deleteLin, Zhaotong; Pan, Wei; Xue, Haoran
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Pre-cuticle DPY-6 acts as a blueprint for aECM periodic organization in C. elegans前角质层DPY-6作为秀丽隐杆线虫aECM周期性组织蓝图的分子基础
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deleteMazzoli, Sophie; Sonntag, Thomas; Cadena, Emma; Valotteau, Claire; Birnbaum, Susanna K.; Sundaram, Meera V.; Pujol, Nathalie
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ZBP1 Drives CD8+ T cell-mediated anti-tumor immunity in head and neck squamous cell carcinomaZBP1 驱动头颈部鳞状细胞癌中 CD8+ T 细胞介导的抗肿瘤免疫
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deleteMin, Yu; Song, Ge; Yang, Lianlian; He, Ling; Xu, Shihong; Gao, Kun; Liu, Zheran; Peng, Xingchen; Dai, Lei
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Design and interpretation of eQTL-GWAS colocalisation studies: Lessons from a large-scale evaluationeQTL-GWAS共定位研究的实验设计与结果解读：大规模评估的经验教训
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deleteReales, Guillermo; Pullin, Jeffrey M.; Manipur, Ichcha; Vigorito, Elena; Wallace, Chris
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Simulated sample splitting approach to address biases due to instrument selection and participant overlap in two-sample Mendelian Randomization studies模拟样本分割方法以解决两样本孟德尔随机化研究中由于仪器选择和参与者重叠导致的偏差
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deleteForde, Amanda; Hemani, Gibran; Ferguson, John
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Spatiotemporal characterization of single-stranded DNA Intermediates after UV Irradiation: I: Post-replication gaps formed during slow growthUV照射后单链DNA中间体的时空表征：I：慢速生长期间形成的复制后间隙
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deleteSharma, Nischal; Cherry, Megan E.; Henry, Camille; Wood, Elizabeth A.; Robinson, Andrew; van Oijen, Antoine; Ghodke, Harshad; Cox, Michael M.
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Spatiotemporal characterization of single-stranded DNA intermediates after UV irradiation: II. Rapid growth and effects of recA and recJUV照射后单链DNA中间体的时空表征：II. 快速生长及recA和recJ的影响
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deleteRipandelli, Remy A. A.; Wood, Elizabeth A.; Robinson, Andrew; van Oijen, Antoine M.; Cox, Michael M.
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The foraging gene coordinates brain and heart networks to modulate socially cued interval timing in Drosophila (vol 21, e1011752, 2015)觅食基因协调大脑和心脏网络以调节果蝇中社会线索触发的间隔计时（vol 21, e1011752, 2015）
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deleteMiao, Hongyu; Li, Wenjing; Huang, Yongwen; Kim, Woo Jae
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Alanine-scanning mutagenesis library of MreB reveals distinct roles for regulating cell shape and viability (vol 22, e1012070, 2026)MreB的丙氨酸扫描诱变文库揭示其在调控细胞形态和存活中的不同作用（卷 22，e1012070，2026）
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deleteMaharjan, Suman; Sloan, Ryan; Lusk, Jada; Bevienguevarr, Rose; Surber, Jacob; Morgenstein, Randy M.
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Why recombination hotspots?为什么重组热点？
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deleteJoseph, Julien; Brazier, Thomas; Raynaud, Marie; Glemin, Sylvain; Baudat, Frederic; de Massy, Bernard; Lartillot, Nicolas; Duret, Laurent
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An intronic variant in Ferredoxin Reductase (FDXR) creates a cryptic exon in Quarter Horses with Equine Juvenile Spinocerebellar AtaxiaFerredoxin Reductase (FDXR)基因内含子变异在患有马青年性脊髓小脑共济失调的夸特马中产生一个隐蔽外显子
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deleteBrown, Briana N.; Dahlgren, Anna R.; Ghosh, Sharmila; Durbin-Johnson, Blythe; Willis, Andrew; Olivas, Cassandra; York, Daniel; Grahn, Robert; Bellone, Rebecca R.; Cortopassi, Gino A.; Miller, Andrew D.; Brown, C. Titus; Woolard, Kevin; Finno, Carrie J.
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KAT6A is essential for developmental control gene expression in neural stem and progenitor cellsKAT6A对于神经干细胞和祖细胞中发育调控基因的表达至关重要
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deleteVoss, Anne K.; Eccles, Samantha; Wichmann, Johannes; Abeysekera, Waruni; Bergamasco, Maria I.; Garnham, Alexandra L.; Ranathunga, Nishika; Yang, Yuqing; Bowden, Rory; Smyth, Gordon K.; Thomas, Tim
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Tumour-driven lipid accumulation in oenocytes reflects systemic lipid alterations肿瘤驱动的脂肪积累在产卵细胞中反映了系统性脂质改变
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deleteLiu, Chang; Golenkina, Sofya; Fahey, Natasha; Kumar, Priya; Cheng, Louise Y.
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Tissue-specific transfer learning improves functional variant and therapeutic target discoveries in breast and prostate cancer组织特异性迁移学习改进了乳腺癌和前列腺癌的功能变异和治疗方法靶点的发现
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deleteLi, Qing; Wang, Dinghao; Zhang, Zilong; Perera, Deshan; Chen, Zhishan; Wen, Wanqing; MacDonald, M. Ethan; Cai, Weijia; Yan, Jun; Shu, Xiao-Ou; Zheng, Wei; Guo, Xingyi; Long, Quan
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Cas9-expressing HC-04 hepatocytes facilitate CRISPR-based analysis of Plasmodium falciparum sporozoite-host interactionsCas9表达HC-04肝细胞促进基于CRISPR的恶性疟原虫子孢子-宿主相互作用分析
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deleteVerzier, Lisa H.; Hesping, Eva; Doerflinger, Marcel; Herold, Marco J.; Boddey, Justin A.
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