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Nuclear β-Catenin under Control

delete2015-06-01
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François Fagotto *
DOI:10.1016/j.devcel.2015.06.005delete
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摘要

摘要

En 中文
During Wnt stimulation, beta-catenin accumulates in the nucleus, where it regulates gene transcription. In this issue of Developmental Cell, Lu et al. (2015) report a mechanism that specifically targets this nuclear pool for degradation, using lysine demethylation as ubiquitination signal.
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Developmental Cell
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