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Optical projection tomography
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DOI：10.1146/annurev.bioeng.6.040803.140210.png)
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Optical projection tomography is anew approach for three-dimensional (3-D) imaging of small biological specimens. It fills an imaging gap between MRI and confocal microscopy, being most suited to specimens that are from 1 to 10 mm across. The tomographic principles of optical projection tomography (OPT) are explained, its most important applications in biomedical research explored, and comparisons drawn of its pros and cons compared to a number of alternative imaging technologies.
Keyword:
3-D imaging
reconstruction
gene expression
fluorescence
phenotyping
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