.png){kind=icon}
返回
Optogenetics Illuminates Applications in Microbial Engineering
.png){kind=icon}
OA
AI
DOI：10.1146/annurev-chembioeng-092120-092340.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Optogenetics has been used in a variety of microbial engineering applications, such as chemical and protein production, studies of cell physiology, and engineered microbe-host interactions. These diverse applications benefit from the precise spatiotemporal control that light affords, as well as its tunability, reversibility, and orthogonality. This combination of unique capabilities has enabled a surge of studies in recent years investigating complex biological systems with completely new approaches. We briefly describe the optogenetic tools that have been developed for microbial engineering, emphasizing the scientific advancements that they have enabled. In particular, we focus on the unique benefits and applications of implementing optogenetic control, from bacterial therapeutics to cybergenetics. Finally, we discuss future research directions, with special attention given to the development of orthogonal multichromatic controls. With an abundance of advantages offered by optogenetics, the future is bright in microbial engineering.
Keyword:
optogenetics
microbial engineering
dynamic control
metabolic engineering
cybergenetics
期刊
IF:
12.8
论文数:
286
被引数:
3.0K
机构
引用论文
The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin FimH.png)
Biochemistry
BiochemistryIF0
PREAI
分享收藏Analysis of hydrogenase 1 levels reveals an intimate link between carbon and hydrogen metabolism in Escherichia coli K-12Microbiology
OAAI
MicrobiologyIF0
OAAI分享收藏Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals用光学编程的基因表达信号表征细菌基因电路动力学NATURE METHODS
NATURE METHODSIF32.1
PREAI
分享收藏Near-infrared Light Responsive Synthetic c-di-GMP Module for Optogenetic Applications用于光遗传学应用的近红外光响应合成c-di-gmp模块OAAI
OAAI分享收藏
查看更多内容