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Persistence clinical studies

delete2014-11-03
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OA
AI
B
Brigitte Cheuvart *
V
Véronique Bianco
M
Magalie Caubet
M
Martine Douha
L
Laurence Fissette
N
Nancy François
A
Anne Sumbul
DOI:10.4161/hv.24168delete
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摘要

摘要

En 中文
Long-term immunity, evaluated by the persistence of antibody titers, is important to assess duration of protection induced by vaccination. This paper aims at drawing awareness on the risk of misinterpreting persistence results in absence of adjustment for missing or left-censored data. Using simulations, the paper shows that repeated measurement models are an appropriate alternative to control the bias associated to unadjusted persistence results.
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期刊

Human Vaccines and Immunotherapeutics 封面图
Human Vaccines and Immunotherapeutics
IF:
3.5
论文数:
6.6K
被引数:
1.7W

机构

G
GlaxoSmithKline
学者数:
268
论文数: 74
被引数: 2.0K
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