PHF7 directs cardiac reprogramming

Elif Eroğlu

doi:10.1038/s41556-021-00684-z

2021-05-03

PRE

Elif Eroğlu

John P. Schell

Kenneth R. Chien *

DOI：10.1038/s41556-021-00684-z

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摘要

En 中文

Epigenetic barriers need to be surmounted in order to increase the efficiency of cardiac reprogramming. A new study now reports that the histone reader PHF7 enhances cardiac reprogramming via recruiting the chromatin remodelling SWI/SNF complex and key transcription factors to the cardiac super enhancers.

Keyword:

REGENERATION

CELLS

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期刊

Nature Cell Biology

IF:

19.1

论文数:

6.2K

被引数:

4.8W

机构

Karolinska Institutet

学者数:

5.8W

论文数: 4.8W

被引数: 7.1W

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