.png){kind=icon}
返回
Photoactivatable Anthracenes
.png){kind=icon}
PRE
AI
DOI：10.1021/jo5004482.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Fifteen substituted maleimide cycloadducts of anthracene derivatives were synthesized in one or two steps from available precursors in yields ranging from 32 to 63%. They differ in the nature of the group on the maleimide nitrogen atom and of the substituents on the anthracene platform. In all instances, the introduction of a maleimide bridge across positions 9 and 10 of the anthracene skeleton isolates electronically its peripheral phenylene rings and suppresses its characteristic fluorescence. The cycloadducts with a 4-(dimethylamino)phenyl group on the maleimide nitrogen atom undergo retro-cycloaddition upon ultraviolet illumination with quantum yields ranging from 0.001 to 0.01. This structural transformation restores the aromatic character of the central ring of the oligoacene chromophore and activates its emission with fluorescence quantum yields ranging from 0.07 to 0.85. Thus, this particular choice of building blocks for the construction of photoresponsive compounds can translate into viable operating principles for fluorescence activation and, ultimately, lead to the realization of valuable photoactivatable fluorophores for imaging applications.
Keyword:
PHOTOCHEMICAL-SYNTHESIS
ALPHA-DIKETONES
FLUORESCENCE
CHEMISTRY
PHOTOGENERATION
PHOTOPHYSICS
MECHANISMS
PRECURSORS
MICROSCOPY
MOLECULES
期刊
IF:
3.6
论文数:
5.4W
被引数:
8.8W
机构
引用论文
Use of caged fluorochromes to track macromolecular movement in living cells.png)
TRENDS IN CELL BIOLOGY
TRENDS IN CELL BIOLOGYIF18.1
PREAI
分享收藏Homogeneous azeotropic distillation in an energy- and mass-integrated pressure swing column system
PREAI
分享收藏分享收藏
查看更多内容