.png){kind=icon}
返回
Preeclampsia is associated with a decrease in plasma coenzyme Q10 levels
.png){kind=icon}
PRE
AI
DOI：10.1016/j.freeradbiomed.2003.08.004.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Preeclampsia is a common (similar to7% of all pregnancies) disorder of human pregnancy in which the normal hemodynamic response to pregnancy is compromised. Despite many years of intensive research, the pathogenesis of preeclampsia is still not fully understood. The objective of the present study was to investigate the concentration of coenzyme Q10 in normal pregnancy and preeclampsia. Pregnant women (n = 18), women with preeclampsia. (n = 12), and nonpregnant normotensive women (n = 22) were included. Plasma levels of coenzyme Q10 were measured by high-performance liquid chromatography. Plasma coenzyme Q10 levels were significantly higher in normal pregnant women (mean = 1.08, SEM = 0.08 umol/l; p < .005) in comparison to nonpregnant women (mean = 0.86, SEM = 0.16 umol/1) and women with preeclampsia (mean = 0.7, SEM = 0.03 umol/l; p < .0001). These results demonstrated that during preeclampsia there is a significant decrease in plasma levels of coenzyme Q10 compared to normal pregnant women, and compared to those who are not pregnant. (C) 2003 Elsevier Inc.
Keyword:
coenzyme Q10
pregnancy
preeclampsia
oxidative stress
free radicals
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
8.2
论文数:
2.1W
被引数:
6.6W
机构
暂无机构信息
引用论文
Plasma membrane NADH-coenzyme Q0 reductase generates semiquinone radicals and recycles vitamin E homologue in a superoxide-dependent reaction.png)
FEBS LETTERS
OAAI
FEBS LETTERSIF3
OAAI分享收藏分享收藏Clinical development of a recombinant Ebola vaccine in the midst of an unprecedented epidemicVaccine
VaccineIF0
PREAI
分享收藏分享收藏
查看更多内容