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Free Radical Biology and Medicine 封面图

Free Radical Biology and Medicine

IF8.2
论文数27761
被引数53607
期刊论文 27761
发表时间
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The stoichiometry trap in cysteine redox biology半胱氨酸氧化还原生物学中的化学计量陷阱
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-28
delete0
deleteOAAI
deleteKate S. Carroll
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Convergent Cardioprotection through Distinct Nitric Oxide and Carbon Monoxide Signaling Pathways after Myocardial Infarction心肌梗死后通过不同的氮氧化物和一氧化碳信号通路实现汇聚性心脏保护
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-27
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deleteOAAI
deleteMartina Cebova; Michaela Kosutova; Andrej Barta; Katarina Bujnova; Olga Pechanova
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Phenylacetylglutamine restrains epithelial ferroptosis in intestinal ischemia–reperfusion by coupling lipid droplet–mitochondria remodeling to metabolic execution苯乙酰谷氨酰胺通过将脂滴-线粒体重塑与代谢执行偶联，抑制肠缺血再灌注中的上皮铁死亡
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-26
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deleteXiaoguo Weng; Yutong Yin; Zhi Xia; Meizi Zheng; Shujie Wang; Dian Chen; Xiaoyao Li; Huimin Liu; Rong Chen; Qingtao Meng
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Polycyclic aromatic hydrocarbons from diesel exhaust particles suppress neurite outgrowth via cell-surface laminin receptor binding, H2O2 redox signaling, and RhoA activation柴油尾气颗粒中的多环芳烃通过细胞表面层粘连蛋白受体结合、H2O2氧化还原信号通路和RhoA激活抑制轴突生长
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-24
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PREAI
deleteRayudu Gopalakrishna; Charles Hoang; Jennifer Aguilar; Roshni Sharma; Genna Kang; Dylan Pham; Anika Seshadri; Halle Wahlgren; Tammy Lee; Angela Tang-Tan; Kristina Shkirkova; Henry Jay Forman; William J. Mack
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Dioscin attenuates aniline-induced liver injury by targeting the ACOT2-mediated ROS–JAK2/STAT3–CLN5 axis and restoring mitochondrial fatty acid oxidation and lysosomal lipophagyDioscin通过靶向ACOT2介导的ROS–JAK2/STAT3–CLN5轴并恢复线粒体脂肪酸氧化和溶酶体脂质自噬来减轻苯胺诱导的肝损伤
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-24
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PREAI
deleteYuechen Xing; Bo Zhang; Yueru Chen; Huayuan Wang; Suan Yu; Lili Chen; Yue Wang
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Promoting KAT5-Mediated CUL5 Lactylation to Downregulate MAVS/NLRP3 Signaling in the Hippocampus: The Novel Mechanisms Underlying Hydrogen Sulfide-Ameliorated Cognitive Dysfunction in Parkinson's Disease促进KAT5介导的CUL5乳酰化以下调海马体中MAVS/NLRP3信号通路：硫化氢改善帕金森病认知功能障碍的新机制
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-22
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PREAI
deleteWen Hu; Wu Jiang; Wen-Jia Luo; Yong Long; Yu Hu; Wei Zou; Ping Zhang; Xiao-Qing Tang
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Corrigendum to “Peroxynitrite activates NLRP3 inflammasome and contributes to hemorrhagic transformation and poor outcome in ischemic stroke with hyperglycemia” [Free Radic. Biol. Med. 165, (2021), 171–183]勘误：“Peroxynitrite activates NLRP3 inflammasome and contributes to hemorrhagic transformation and poor outcome in ischemic stroke with hyperglycemia” [Free Radic. Biol. Med. 165, (2021), 171–183]
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-22
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PREAI
deleteHansen Chen; Binghe Guan; Shuang Chen; Dan Yang; Jiangang Shen
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Neuronal oxidative stress and mitophagy contribute to microglial inflammation in radiation-induced brain injury神经元氧化应激和线粒体自噬参与辐射诱导脑损伤中的小胶质细胞炎症
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-21
delete0
PREAI
deleteWeirui Chen; Xiaoxin Ye; Anbang Ren; Anan xu; Rong Li
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PRDX4 attenuates mitochondrial dysfunction by targeting CALR/SERCA2 interaction to suppress mitochondrial apoptosis in laryngeal squamous cell carcinomaPRDX4通过靶向CALR/SERCA2相互作用抑制喉鳞状细胞癌的线粒体凋亡以减轻线粒体功能障碍
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-21
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PREAI
deletePengyan Liu; Wenjing Li; Yujian Teng; Yaohui Liu; Pengjiao Liu; Shunpeng Wang; Yaoyao Dong; Tiedan Xu; Yushan Ding; Jiaxue Ni; Linli Tian
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Lycorine ameliorates MASH by targeting ACSL4 to regulate lipid metabolism and inhibit ferroptosis硫代秋水仙碱通过靶向ACSL4调节脂质代谢并抑制铁死亡以改善MASH
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-21
delete0
PREAI
deleteFei Yu; Lvjun Zhang; Yanqiu Zhang; Yang Cheng; Yingrong Leng; Shengtao Ye; Ying Zheng; Hao Zhang; Lingyi Kong
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Laminin-α2 deficiency is associated with altered multiorgan redox signatures层粘连蛋白-α2缺乏与多器官氧化还原特征改变相关
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-21
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deleteSusana G. Martins; Mafalda Pita; Sharadha Dayalan Naidu; Vanessa Ribeiro; Hebe Lameirão-Ferreira; Carlos Gravato; Albena T. Dinkova-Kostova; Sólveig Thorsteinsdóttir; Ana Rita Carlos
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Elastin-derived peptide VGVAPG induces redox-associated pro-inflammatory activation and early disease-associated microglia (DAM) molecular profile in a human microglia-neuron in vitro model involving NEU1/TLR4-related signaling弹性蛋白衍生肽VGVAPG在涉及NEU1/TLR4相关信号的人类小胶质细胞-神经元体外模型中诱导氧化还原相关的促炎激活和早期疾病相关小胶质细胞（DAM）分子谱
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-21
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deleteBartosz Skóra; Konrad A. Szychowski
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Selective NRF2 target induction despite falling NFE2L2 transcription across the MASLD spectrum: implications for marginal donor grafts and KEAP1-targeted therapy尽管NFE2L2转录在MASLD谱系中下降，但仍能选择性诱导NRF2靶基因：对边缘供体移植物和KEAP1靶向治疗的启示
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-20
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PREAI
deleteSally Campbell; Róisín O'Reilly; Ola Ahmed; Matt McElheron; William C. Chapman; Cliona O'Farrelly
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Mcu upregulation triggers mitochondrial oxidative stress and cardiomyocyte injury after myocardial infarction yet is suppressed by Fto and Ythdf2 in an m6A-dependent mannerMcu上调触发心肌梗死后线粒体氧化应激和心肌细胞损伤，但被Fto和Ythdf2以m6A依赖的方式抑制
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-20
delete0
PREAI
deleteRuolan Chen; Xuezhe Wang; Luning Qin; Zhijun Liu; Chunjuan Yu; Xiaoxia Li; Zhe Zhang; Fanghao Yang; Huhu Zhang; Hongtao Lan; Xinchi Luan; Xiaojian Xu; Changan Qu; Bing Li; Gang Li; Xian-Ming Chu
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Deubiquitination of WBP11 governs OPLAH-mediated glutathione biosynthesis to suppress triple programmed cell death in prostate cancerWBP11的去泛素化调控OPLAH介导的谷胱甘肽生物合成以抑制前列腺癌中的三重程序性细胞死亡
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-20
delete0
PREAI
deleteXuefen Zhuang; Wanying He; Jiangyu Zhang; Zixuan Wang; Kaixing Zheng; Yanqi Zhuang; Zilong Song; Wenshuang Sun; Zhenlong Shao; Xiaodong Fu; Yuning Liao
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Systemic oxidative stress in patients with Alzheimer's disease阿尔茨海默病患者中的系统性氧化应激
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-20
delete0
deleteOAAI
deleteN.A. Verwey; M. Kloppenburg-Lagendijk; M.L.C. Bulthuis; W. Ferket; A.M. Koning; H. van Goor; A.R. Bourgonje
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Targeting PRDX1-G6PD Interaction Promotes a Metabolic Vulnerability and Redox Imbalance in Triple-Negative Breast Cancer靶向PRDX1-G6PD相互作用促进三阴性乳腺癌的代谢脆弱性和氧化还原失衡
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-18
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PREAI
deleteHongru Tao; Ningyun Liu; Ziang Hu; Yixuan Xu; Heng Xu; Yuanyuan Zhang; Cheng Luo
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Transient but not sustained p53 activation by targeting METTL3 prevents radiation-induced intestinal injury through dual-regulation of revival stem cells靶向METTL3可短暂而非持续激活p53，通过双重调控复苏干细胞来预防辐射诱导的肠道损伤
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-17
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PREAI
deleteRuiqiu Zhu; Mingyue Li; Chengzhi Liu; Defu Kong; Jialu Qian; Ming Li; Ye Tian; Liwei Xie; Shang Cai
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MLKL Orchestrates ER-Mitochondria Stress to Drive Dendritic Cell Pyroptosis and Immunoparalysis in SepsisMLKL调控内质网-线粒体应激以驱动树突状细胞焦亡及免疫麻痹的发生于脓毒症中
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-17
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PREAI
deleteYimeng Wang; Bing Sun; Huayong Chen; Jiewei Luo; Yingping Cao
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Bisphenol A induces hepatotoxicity via a LAMP3-dependent impairment of mitophagic processing and reduced PI3K-AKT-mTOR signaling双酚A通过LAMP3依赖性损害线粒体自噬加工和降低PI3K-AKT-mTOR信号通路诱导肝毒性
deleteFree Radical Biology and Medicine
IF8.2
delete2026-10-15
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PREAI
deleteBin Lu; Yuhui Shi; Xingzhi Chen; Yongheng Huang; Jie Ding; Mingxing Xu; Yuan Feng; Nan Lin
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