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PROTAC-ing tuberculosis

delete2024-05-23
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PRE
AI
D
Delia Preti *
V
Valentina Albanese
P
Peggy Marconi
DOI:10.1038/s41589-024-01624-2delete
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摘要

摘要

En 中文
Targeted protein degradation has emerged as a promising approach in drug discovery, harnessing a cell's intrinsic machinery to eliminate disease-related proteins. Now, a study paves the way to translating this technology into potential anti-mycobacterial therapies, by exploiting the bacterial protein-degradation complex.

期刊

Nature Chemical Biology 封面图
Nature Chemical Biology
IF:
13.7
论文数:
4.8K
被引数:
3.3W

机构

U
University of Ferrara
学者数:
1.4W
论文数: 1.1W
被引数: 12
引用论文

引用论文

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errJunk, Lukas; Schmiedel, Volker M.; Guha, Somraj; Fischel, Katharina; Greb, Peter; Vill, Kristin; Krisilia, Violetta; van Geelen, Lasse; Rumpel, Klaus; Kaur, Parvinder; Krishnamurthy, Ramya V.; Narayanan, Shridhar; Shandil, Radha Krishan; Singh, Mayas; Kofink, Christiane; Mantoulidis, Andreas; Biber, Philipp; Gmaschitz, Gerhard; Kazmaier, Uli; Meinhart, Anton; Leodolter, Julia; Hoi, David; Junker, Sabryna; Morreale, Francesca Ester; Clausen, Tim; Kalscheuer, Rainer; Weinstabl, Harald; Boehmelt, Guido
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