arrow
返回

Quality control in LC-MS/MS

delete2011-02-07
delete37
PRE
AI
T
Thomas Köcher *
P
Peter Pichler
R
Remco Swart
K
Karl Mechtler
DOI:10.1002/pmic.201000578delete
delete原文链接
delete原文求助
delete分享
delete收藏
摘要

摘要

En 中文
In the last 15 years, MS-based protein characterization has expanded at a rapid rate. This success is built upon constantly improving instrumentation and a variety of ingenious methods applied to numerous biological questions. However, the reproducibility of mass spectrometric results is considered by many as insufficient. In part, inadequate quality control might be responsible for the lack of reproducibility. Quality control is rarely discussed in scientific publications. Here, we briefly present measures undertaken in our laboratory to foster a general discussion of the subject.
Keyword:
LC-MS/MS
Quality control
Systems Biology

期刊

Proteomics 封面图
Proteomics
IF:
3.9
论文数:
7.6K
被引数:
1.1W

机构

V
vienna biocenter (vbc)
学者数:
2.8K
论文数: 1.6K
被引数: 7
R
Research Institute of Molecular Pathology
学者数:
495
论文数: 322
被引数: 1.9K
U
University of Vienna
学者数:
1.7W
论文数: 1.6W
被引数: 40
学者 查看更多机构
引用论文

引用论文

Reporting protein identification data - The next generation of guidelines
err2006-05-01
err221
errOAAI
errBradshaw, RA; Burlingame, AL; Carr, S; Aebersold, R
err分享
err收藏
Analysis and validation of proteomic data generated by tandem mass spectrometry
err2007-09-27
err616
PREAI
errNesvizhskii, Alexey I.; Vitek, Olga; Aebersold, Ruedi
err分享
err收藏
A statistical model for identifying proteins by tandem mass spectrometry
err2003-07-15
err4.5K
PREAI
errNesvizhskii, AI; Keller, A; Kolker, E; Aebersold, R
err分享
err收藏
Preventing Carryover of Peptides and Proteins in Nano LC-MS Separations
err2009-06-19
err74
PREAI
errMitulovic, Goran; Stingl, Christoph; Steinmacher, Ines; Hudecz, Otto; Hutchins, James R. A.; Peters, Jan-Michael; Mechtler, Karl
err分享
err收藏
Video-assisted thoracoscopic surgery using mobile computed tomography: New method for locating of small lung nodules
err2014-06-20
err0
errOAAI
errKazuto Ohtaka; Yasuhiro Takahashi; Kichizo Kaga; Naoto Senmaru; Yoshihisa Kotani; Yoshiro Matsui
err分享
err收藏
err分享
err收藏
Interpretation of Shotgun Proteomic Data
err2005-10-01
err944
errOAAI
errNesvizhskii, AI; Aebersold, R
err分享
err收藏
学者 查看更多内容