Recent developments in phasing and structure refinement for macromolecular crystallography

doi:10.1016/j.sbi.2009.07.014

Recent developments in phasing and structure refinement for macromolecular crystallography

2009-10-01

27

OA

AI

Ralf W. Grosse‐Kunstleve

Thomas C. Terwilliger

DOI：10.1016/j.sbi.2009.07.014

原文链接

查看原文

摘要

En 中文

Central to crystallographic structure solution is obtaining accurate phases in order to build a molecular model, ultimately followed by refinement of that model to optimize its fit to the experimental diffraction data and prior chemical knowledge. Recent advances in phasing and model refinement and validation algorithms make it possible to arrive at better electron density maps and more accurate models.

Keyword:

ANISOTROPIC THERMAL PARAMETERS

NORMAL-MODE REFINEMENT

MAXIMUM-LIKELIHOOD

MOLECULAR-REPLACEMENT

X-RAY

DENSITY-MODIFICATION

STRUCTURE VALIDATION

ACCURACY

INFORMATION

DIFFRACTION

Recent developments in phasing and structure refinement for macromolecular crystallography

摘要

AI总结

期刊

机构

引用论文