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Refining sequence-to-expression modelling with chromatin accessibility
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DOI：10.1093/bioinformatics/btag199.png)
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Abstract
En 中文
Sequence-to-expression models typically do not consider chromatin accessibility, a major factor limiting gene regulation. We hypothesized that supplying accessibility as an input feature would allow a sequence-to-expression model to focus on important open regions of the genome.
Keywords:
sequence-to-expression model
chromatin accessibility
gene regulation
genomic regions
regulatory features
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