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Robbing from the pore
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DOI：10.1038/ncb0304-177.png)
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How do you build a sorting machine that can function with less than half of its sorting components? This problem challenges our understanding of nucleocytoplasmic transport after the finding that yeast can survive with nuclear pore complexes (NPCs) containing only half their original mass of transport-factor-binding domains.
Keyword:
NUCLEAR IMPORT
COMPLEX
NUCLEOPORINS
TRANSPORT
GRADIENT
AFFINITY
PATHWAY
BINDING
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Disorder in the nuclear pore complex: The FG repeat regions of nucleoporins are natively unfolded
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OAAI分享收藏分享收藏Gradient of increasing affinity of importin β for nucleoporins along the pathway of nuclear importOAAI
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