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摘要
En 中文
Cyclic tetrapeptides (CTPs) have great potential for materials and therapeutics; however, synthesizing these molecules remains a significant challenge. Now, an enzyme has been developed that enables efficient N-to-C cyclization of linear tetrapeptidyl substrates to form structurally diverse CTPs.
期刊
IF:
13.7
论文数:
4.8K
被引数:
3.3W
机构
引用论文
A trans-Acting Cyclase Offloading Strategy for Nonribosomal Peptide Synthetases
ACS CHEMICAL BIOLOGY
IF3.8
Investigation of Penicillin Binding Protein (PBP)-like Peptide Cyclase and Hydrolase in Surugamide Non-ribosomal Peptide BiosynthesisSurugamide非核糖体肽生物合成中青霉素结合蛋白 (PBP) 样肽环化酶和水解酶的研究
Biocatalytic cyclization of small macrolactams by a penicillin-binding protein-type thioesterase
NATURE CHEMICAL BIOLOGY
IF13.7

