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Cell Chemical Biology 封面图

Cell Chemical Biology

IF7.2
论文数1770
被引数9110
期刊论文 1770
发表时间
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Shared α-helix chimeraffibodies enable linker-free bispecific protein design共享α-螺旋嵌合affibody蛋白实现无连接蛋白双特异性设计
deleteCell Chemical Biology
IF7.2
delete2026-10-26
delete0
PREAI
deleteXiaohui Qiu; Xu Chen; Zekai Zeng; Yongxiao Li; Jianye Yuan; Chang Xu; Jiaqi Wang; Xinpei Wang; Ruizhi Lai; Youjian Zhou; Jinghuan Mao; Yiqi Wang; Qiankun Liao; Zhe Wang; Junqing Wang
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Genetic dissection of rapid proteolysis identifies TXNDC15 as a key factor of ERAD and lipid homeostasis对快速蛋白降解的遗传解析确定了TXNDC15为内质网相关降解和脂质稳态的关键因子
deleteCell Chemical Biology
IF7.2
delete2026-10-22
delete0
PREAI
deleteYuyang Liu; Michelle Yinfei Yaochai; Shanshan Liu; Hanan Alwaseem; Kıvanç Birsoy
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Proteasome inhibition bidirectionally regulates ferroptosis sensitivity蛋白酶体抑制双向调节铁死亡敏感性
deleteCell Chemical Biology
IF7.2
delete2026-10-21
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PREAI
deleteMagdalena B. Murray; Rishi Upadhyay; Krystina J. Szylo; Aastha Gautam; Judith Goncalves; Giovanni Forcina; Ananya Vinayak; Onn Brandman; Scott J. Dixon
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Small-molecule modulation of VDAC enhances glucose-stimulated insulin secretion by promoting ATP flux小分子调控VDAC通过促进ATP流增强葡萄糖刺激的胰岛素分泌
deleteCell Chemical Biology
IF7.2
delete2026-10-20
delete0
PREAI
deleteKohichi Matsunaga; Kaori Honda; Muneeb Ali; Abdul Hameed; Ryota Inoue; Takahiro Tsuno; Tatsuya Kin; A. M. James Shapiro; Hideru Obinata; Yasumitsu Kondoh; Zaheer Ul-Haq; Hiroyuki Osada; Tetsuro Izumi; Jun Shirakawa
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Selective USP32 inhibition reveals endosomal ubiquitin signaling and enables cell-permeable activity-based probes选择性USP32抑制揭示了内体泛素信号并使细胞渗透性活性基探针成为可能
deleteCell Chemical Biology
IF7.2
delete2026-10-19
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deleteOAAI
deleteStephan Scherpe; Febe C. Vermue; Vito Pol; Raymond Kooij; Adán Pinto-Fernández; Rayman T.N. Tjokrodirijo; Darragh P. O’Brien; Iolanda Vendrell; Dharjath S. Hameed; Ilana Berlin; Peter A. van Veelen; Benedikt M. Kessler; Paul P. Geurink; Aysegul Sapmaz
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The expanding biology of post-translational modifications翻译：翻译后修饰的生物学研究进展
deleteCell Chemical Biology
IF7.2
delete2026-10-15
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PREAI
deleteGeorge Burslem
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Targeting protein arginine methyltransferases to enhance cancer immunotherapy靶向精氨酸甲基转移酶以增强癌症免疫治疗
deleteCell Chemical Biology
IF7.2
delete2026-10-15
delete0
PREAI
deleteNivine Srour; Chunxiao Zhao; Stéphane Richard
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Protein arginine methylation rewires molecular interactions蛋白质精氨酸甲基化重编程分子相互作用
deleteCell Chemical Biology
IF7.2
delete2026-10-15
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deleteJoseph D. DeAngelo; Aliza M. Silverstein; David Shechter
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Meet the authors: Cameron Douglas and Ciaran Seath与作者见面：Cameron Douglas 和 Ciaran Seath
deleteCell Chemical Biology
IF7.2
delete2026-10-15
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PREAI
deleteCameron Douglas; Ciaran Seath
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Structural basis and rational engineering of a thermophilic Cas13a for robust RNA detection热稳定性Cas13a的结构基础及其用于鲁棒性RNA检测的理性工程改造
deleteCell Chemical Biology
IF7.2
delete2026-10-13
delete0
PREAI
deleteSeye J. Oladeji; Diego H. Gonzalez; Xiangyu Deng; Zheng You; Yuxuan Zhang; Devin A. Golla; Jamie Smith; Yi Zhang; Xue Gao; Peter B. Lillehoj; Yang Gao
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Disease-causing helix-8 mutations reprogram parathyroid hormone receptor-1 effector selectivity致病性螺旋-8突变重编程甲状旁腺激素受体-1效应器选择性
deleteCell Chemical Biology
IF7.2
delete2026-10-12
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deleteJakob Höppner; Tomasz Maciej Stepniewski; Thomas Dean; Miguel Diéguez-Eceolaza; Lauren My-Linh Tran; Samuel H. Gellman; Ross W. Cheloha; Asuka Inoue; Jana Selent; Harald Jüppner; Thomas J. Gardella
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A modular platform for in cellulo target engagement profiling of chromatin reader inhibitors一种用于在细胞内进行染色质读取器抑制剂靶点结合分析的模块化平台
deleteCell Chemical Biology
IF7.2
delete2026-10-09
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PREAI
deleteDavide C. Recchia; Richard Cardoso da Silva; Mathilde Noël; Douwe ten Bulte; Ifigeneia Thomopoulou; Niklas Kupfer; Angela Topic; Sara Giuliani; Rodrigo Villaseñor; Tuncay Baubec
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Disrupting BRD4-BD1-p62 engagement restores protective autophagy破坏BRD4-BD1-p62相互作用可恢复保护性自噬
deleteCell Chemical Biology
IF7.2
delete2026-10-08
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PREAI
deleteJifa Zhang; Yu Cao; Chengyong Wu; Yang Li; Juncheng Chen; Doudou Wang; Yao Xiao; Binghan Xue; Cailing Gan; Xin Chen; Yuxi Wang; Tinghong Ye; Liang Ouyang
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Targeting ZDHHC15-mediated S-acylation of CD155 reactivates anti-tumor immunity靶向ZDHHC15介导的CD155 S-酰化可重新激活抗肿瘤免疫
deleteCell Chemical Biology
IF7.2
delete2026-10-07
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PREAI
deleteXuanpu Zhang; Jie Zou; Jian Lin; Yu Xiao; Yue Zhu; Bokan Chen; Ziye Zhu; Yizhen Ding; Xinmei Zhou; Yinghong Yang; Xiaoyi Wang; Weijie Zhang; Min Zhang; Xia Lin; Pinglong Xu; Baoen Chen
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Non-enzymatic protein modifications at the interface of metabolism and immunity代谢与免疫界面上的非酶促蛋白质修饰
deleteCell Chemical Biology
IF7.2
delete2026-10-06
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PREAI
deleteNicole S. Walker; James J. Galligan; Yael David; Anna Knörlein
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Arginine methylation in immunoregulation: Mechanisms and therapeutic targeting精氨酸甲基化在免疫调节中的作用：机制与治疗靶向
deleteCell Chemical Biology
IF7.2
delete2026-10-05
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PREAI
deleteSong-Iee Han; Sachiko Toma-Fukai; Jun-Dal Kim; Koichiro Kako; Hiroaki Daitoku; Akiyoshi Fukamizu
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ESCAPE enables receptor-specific chemogenetic dissection of GPCR signalingESCAPE实现GPCR信号通路的受体特异性化学遗传学解析
deleteCell Chemical Biology
IF7.2
delete2026-10-02
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PREAI
deleteYuma Matsuoka; Hajime Inoue; Tatsuki Hori; Duy Phuoc Tran; Akio Kitao; Hayate Suzuki; Seiya Mizuno; Satoru Takahashi; Tomohiro Doura; Shigeki Kiyonaka
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Hepatic FoxO1 loss leads to pancreatic β cell deficiency via liver-derived C18/22/24 ceramides肝脏FoxO1缺失通过肝脏来源的C18/22/24神经酰胺导致胰腺β细胞缺乏
deleteCell Chemical Biology
IF7.2
delete2026-10-01
delete0
PREAI
deleteYulong Gong; Qisheng Lu; Xuehui Li; Guoli Han; Xiaochen Ma; Yulong Liu; Longwei Xi; Chaofan Wang; Gang Zhai; Zhimin Zhang; Haokun Liu; Junyan Jin; Yunxia Yang; Xiaoming Zhu; Zhan Yin; Yonghua Sun; Wenbiao Chen; Shouqi Xie; Dong Han
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Rational design of protease-resistant lipopeptides for combating antibiotic-resistant bacteria蛋白酶抗性脂肽的理性设计以对抗抗药性细菌
deleteCell Chemical Biology
IF7.2
delete2026-09-30
delete0
PREAI
deleteJiajun Wang; Haoran Xu; Yu Sun; Na Dong; Weikang Yu; Shiqi He; Anshan Shan
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Post-translational modifications in bacteria: From identification to function细菌中的翻译后修饰：从鉴定到功能
deleteCell Chemical Biology
IF7.2
delete2026-09-29
delete0
deleteOAAI
deleteAshleigh L. Dale; Melanie Y. White; Stuart J. Cordwell
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