Structural alignments to design functional RNAs

Gina El Nesr

doi:10.1038/s43588-026-01028-3

2026-07-30

PRE

Gina El Nesr *

DOI：10.1038/s43588-026-01028-3

原文链接

原文求助

摘要

En 中文

一种新方法通过学习结构相似分子的比对设计RNA序列，生成经实验验证的适配体和核酶。

期刊

Nature Computational Science

IF:

18.3

论文数:

3.1K

被引数:

4.0K

机构

stanford university

学者数:

1.1W

论文数: 4.3K

被引数: 0

引用论文

Structure-alignment-driven cross-graph modeling for functional RNA design 结构对齐驱动的交叉图建模用于功能RNA设计

Nature Computational Science

IF18.3

2026-07-30

PREAI

Shengfan Wang; Jun Wang; Xiaojian Liu; Weimin Zhu; Jiaqi Huang; Yiming Xue; Junchi Yan; Hong-Bin Shen; Jie Song; Xiaoyong Pan

Highly accurate protein structure prediction with AlphaFold 基于AlphaFold的高精度蛋白质结构预测

Nature

IF0

2021-07-15

OAAI

John Jumper; Richard Evans; Alexander Pritzel; Tim Green; Michael Figurnov; Olaf Ronneberger; Kathryn Tunyasuvunakool; Russ Bates; Augustin Žídek; Anna Potapenko; Alex Bridgland; Clemens Meyer; Simon A. A. Kohl; Andrew J. Ballard; Andrew Cowie; Bernardino Romera-Paredes; Stanislav Nikolov; Rishub Jain; Jonas Adler; Trevor Back; Stig Petersen; David Reiman; Ellen Clancy; Michal Zielinski; Martin Steinegger; Michalina Pacholska; Tamas Berghammer; Sebastian Bodenstein; David Silver; Oriol Vinyals; Andrew W. Senior; Koray Kavukcuoglu; Pushmeet Kohli; Demis Hassabis

Structures of artificially designed discrete RNA nanoarchitectures at near-atomic resolution

SCIENCE ADVANCES

IF12.5

2021-09-24

OAAI

Liu, Di; Shao, Yaming; Piccirilli, Joseph A.; Weizmann, Yossi

Advances and opportunities in RNA structure experimental determination and computational modeling

NATURE METHODS

IF32.1

2022-10-06

OAAI

Zhang, Jinsong; Fei, Yuhan; Sun, Lei; Zhang, Qiangfeng Cliff

The past, present and future of de novo protein design 从头蛋白质设计的过去、现在与未来

Nature

IF48.5

2026-04-29

PREAI

Wei Yang; Shunzhi Wang; Gyu Rie Lee; Jason Z. Zhang; Alexis Courbet; David Juergens; Xinru Wang; Thomas Schlichthaerle; Mohamad Abedi; Robert Ragotte; Linna An; Indrek Kalvet; Sam Pellock; Ljubica Mihaljevic; Cameron Glasscock; Arvind Pillai; Adam Broerman; Nathan Ennist; Ella Haefner; Nora McNamara-Bordewick; Ian Haydon; Lance Stewart; Gaurav Bhardwaj; David Baker