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Ternary DNA computing using 3 x 3 multiplication matrices

delete2015-01-01
delete34
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OA
AI
R
Ron Orbach
S
Sivan Lilienthal
M
Michael L. Klein
R
R. D. Levine
F
F. Remacle
I
Itamar Willner *
DOI:10.1039/c4sc02930edelete
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摘要

摘要

En 中文
Non-Boolean computations implementing operations on multi-valued variables beyond base 2 allow enhanced computational complexity. We introduce DNA as a functional material for ternary computing, and in particular demonstrate the use of three-valued oligonucleotide inputs to construct a 3 x 3 multiplication table. The system consists of two three-valued inputs of -1; 0; + 1 and a fluorophore/quencher functional hairpin acting as computational and reporter module. The interaction of the computational hairpin module with the different values of the inputs yields a 3 x 3 multiplication matrix consisting of nine nanostructures that are read out by three distinct fluorescence intensities. By combining three different hairpin computational modules, each modified with a different fluorophore/quencher pair, and using different sets of inputs, the parallel operation of three multiplication tables is demonstrated.
Keyword:
LOGIC GATES
CIRCUITS
COMPUTATION
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期刊

Chemical Science 封面图
Chemical Science
IF:
7.4
论文数:
1.7W
被引数:
9.3W

机构

U
University of Liege
学者数:
1.7W
论文数: 1.4W
被引数: 2.1W
H
Hebrew University of Jerusalem
学者数:
2.8W
论文数: 2.3W
被引数: 2.7W
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