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The Proteomics Identifications database: 2010 update

delete2009-11-10
delete206
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OA
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J
Juan Antonio Vizcaíno
R
Richard G. Côté
F
Florian Reisinger
H
Harald Barsnes
J
Joseph Foster
J
Jonathan Rameseder
H
Henning Hermjakob
L
Lennart Martens *
DOI:10.1093/nar/gkp964delete
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摘要

摘要

En 中文
The Proteomics Identifications database (PRIDE, http://www.ebi.ac.uk/pride) at the European Bioinformatics Institute has become one of the main repositories of mass spectrometry-derived proteomics data. For the last 2 years, PRIDE data holdings have grown substantially, comprising 60 different species, more than 2.5 million protein identifications, 11.5 million peptides and over 50 million spectra by September 2009. We here describe several new and improved features in PRIDE, including the revised submission process, which now includes direct submission of fragment ion annotations. Correspondingly, it is now possible to visualize spectrum fragmentation annotations on tandem mass spectra, a key feature for compliance with journal data submission requirements. We also describe recent developments in the PRIDE BioMart interface, which now allows integrative queries that can join PRIDE data to a growing number of biological resources such as Reactome, Ensembl, InterPro and UniProt. This ability to perform extremely powerful across-domain queries will certainly be a cornerstone of future bioinformatics analyses. Finally, we highlight the importance of data sharing in the proteomics field, and the corresponding integration of PRIDE with other databases in the ProteomExchange consortium.
Keyword:
PUBLIC REPOSITORY
MS REPOSITORIES
PROTEIN
PRIDE
GENERATION
RESOURCE
ELEGANS
SERVICE
TOOLS
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Nucleic Acids Research 封面图
Nucleic Acids Research
IF:
13.1
论文数:
3.6W
被引数:
29.0W

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E
european molecular biology laboratory (embl)
学者数:
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论文数: 5.1K
被引数: 31
U
university of bergen
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论文数: 146
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