logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回

Towards a decentralized future for open-science databases

delete2026-05-19
delete0
PRE
AI
G
Gaurav Sharma *
V
Viorel Munteanu
N
Nika Mansouri Ghiasi
U
Utkarsha Mahanta
J
Jineta Banerjee
S
Susheel Varma
L
Luca Foschini
K
Kyle Ellrott
O
Onur Mutlu
D
Dumitru Ciorbă
R
Roel A. Ophoff
V
Viorel Bostan
J
Jason H. Moore
D
Despoina Sousoni
A
Arunkumar Krishnan
A
Alexander G. Lucaci
A
Alba Tull
C
Christopher E. Mason
M
Mihai Dimian
G
Gustavo Stolovitzky
F
Fabio G. Liberante
T
Tarás K. Oleksyk
S
Serghei Mangul *
DOI：10.1038/s41588-026-02606-xdelete
delete原文链接
delete原文求助
delete分享
delete收藏
摘要

摘要

En 中文
大型生物数据存储库，尤其是在部署为单个、非镜像实例或受限于狭窄语境时，面临结构脆弱性，从网络攻击到资金中断。我们提出了一种混合框架，整合联邦和去中心化模型，以确保科学数据作为全球公共产品具有韧性、可持续性和FAIR/CARE管理。
Keyword:
decentralized databases
federated learning
open science
data resilience
FAIR principles

期刊

Nature Genetics 封面图
Nature Genetics
IF:
29
论文数:
731
被引数:
241

机构

T
Technical University of Moldova
学者数:
129
论文数: 50
被引数: 239
I
iiser berhampur
学者数:
6
论文数: 5
被引数: 2
O
Oakland University
学者数:
3.7K
论文数: 3.0K
被引数: 2.7K
W
weill cornell medicine
学者数:
2.2K
论文数: 1.0K
被引数: 0
U
university of california los angeles
学者数:
5.3W
论文数: 4.2W
被引数: 89
O
oregon health and science university
学者数:
980
论文数: 408
被引数: 0
E
eth zurich
学者数:
2.3K
论文数: 1.1K
被引数: 0
S
Sage Bionetworks
学者数:
44
论文数: 15
被引数: 914
I
indian institute of technology hyderabad
学者数:
510
论文数: 218
被引数: 0
N
NYU Grossman School of Medicine
学者数:
1.3K
论文数: 559
被引数: 1
C
cedars-sinai health sciences university
学者数:
41
论文数: 15
被引数: 0
W
Wellcome Trust
学者数:
152
论文数: 76
被引数: 9.8K
学者 查看更多机构
引用论文

引用论文

Scientists globally are racing to save vital health databases taken down amid Trump chaos全球科学家正争分夺秒抢救因特朗普混乱局面而被关闭的关键健康数据库。
errNATURE
IF48.5
err2025-02-07
err0
PREAI
errMallapaty, Smriti
err分享
err收藏
Perceptual and technical barriers in sharing and formatting metadata accompanying omics studies在组学研究伴随元数据的共享与格式化方面的感知和技朧障碍
err
IF0
err
err0
PREAI
err
err分享
err收藏
err
IF0
err
err0
PREAI
err
err分享
err收藏
ELIXIR: providing a sustainable infrastructure for life science data at European scale
errBioinformatics
IF0
err2021-06-27
err0
errOAAI
errJennifer Harrow; Rachel Drysdale; Andrew Smith; Susanna Repo; Jerry Lanfear; Niklas Blomberg
err分享
err收藏
Safeguarding the future of biomedical science in the United States保护美国生物医学科学的未来
errCELL
IF42.5
err2025-02-01
err0
PREAI
errManiatis, Tom
err分享
err收藏
The Federated European Genome-Phenome Archive as a global network for sharing human genomics data欧洲联邦基因组-表型档案库作为共享人类基因组数据的全球网络
errNATURE GENETICS
IF0
err2025-03-03
err0
PREAI
errD'Altri, Teresa; Freeberg, Mallory Ann; Curwin, Amy J.; Alonso, Ana; Freitas, Ana T.; Hagwall, Anna; Kerry, Giselle; Kirli, Koray; Kochel, Krzysztof; Kohlbacher, Oliver; Korbel, Jan O.; Leinonen, Jaakko; Oliveira, Jorge S.; Petersen, Kjell; Silva, Mario J.; Stegle, Oliver; Valencia, Alfonso; Viklund, Johan; Guigo, Roderic; Parkinson, Helen; Navarro, Arcadi; Rambla, Jordi; Keane, Thomas M.
err分享
err收藏
Open Science 2.0: Towards a truly collaborative research ecosystem
errPLOS Biology
IF0
err2023-10-19
err0
errOAAI
errRobert T. Thibault; Olavo B. Amaral; Felipe Argolo; Anita E. Bandrowski; Alexandra R, Davidson; Natascha I. Drude
err分享
err收藏
Leveraging European infrastructures to access 1 million human genomes by 2022
errNATURE REVIEWS GENETICS
IF52
err2019-08-27
err57
errOAAI
errSaunders, Gary; Baudis, Michael; Becker, Regina; Beltran, Sergi; Beroud, Christophe; Birney, Ewan; Brooksbank, Cath; Brunak, Soren; Van den Bulcke, Marc; Drysdale, Rachel; Capella-Gutierrez, Salvador; Flicek, Paul; Florindi, Francesco; Goodhand, Peter; Gut, Ivo; Heringa, Jaap; Holub, Petr; Hooyberghs, Jef; Juty, Nick; Keane, Thomas M.; Korbel, Jan O.; Lappalainen, Ilkka; Leskosek, Brane; Matthijs, Gert; Mayrhofer, Michaela Th.; Metspalu, Andres; Navarro, Arcadi; Newhouse, Steven; Nyronen, Tommi; Page, Angela; Persson, Bengt; Palotie, Aarno; Parkinson, Helen; Rambla, Jordi; Salgado, David; Steinfelder, Erik; Swertz, Morris A.; Valencia, Alfonso; Varma, Susheel; Blomberg, Niklas; Scollen, Serena
err分享
err收藏
Decentralized science (DeSci): definition, shared values, and guiding principles去中心化科学 (DeSci)：定义、共享价值观和指导原则。Front. Blockchain 7, 1375763
errFrontiers in Blockchain
IF0
err2024-07-17
err0
PREAI
errLukas Weidener; Cord Spreckelsen
err分享
err收藏
Defending Our Public Biological Databases as a Global Critical Infrastructure
errFrontiers in Bioengineering and Biotechnology
IF0
err2019-04-05
err0
errOAAI
errJacob Caswell; Jason D. Gans; Nicholas Generous; Corey M. Hudson; Eric Merkley; Curtis Johnson; Christopher Oehmen; Kristin Omberg; Emilie Purvine; Karen Taylor; Christina L. Ting; Murray Wolinsky; Gary Xie
err分享
err收藏
学者 查看更多内容