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A computational model of activities performance decrease in Alzheimer's disease
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DOI：10.1016/j.ijmedinf.2007.04.002.png)
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Abstract
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This article presents a computational model and a simulation of the decrease of performance in daily living activities due to Alzheimer's disease. The framework offered by the cognitive architecture ACT-R is used to develop the model. Typical errors committed in performing tasks by Alzheimer patients are modelled thanks to different parametrisable memory mechanisms of ACT-R and the disease evolution is represented by the increase of errors in the execution of the task. The model is applied to a cooking activity. Simulation of 100 subjects shows results similar to those realised in a standardized assessment with human subjects. We conclude on the need to introduce executive mechanisms in the modelling of behaviours associated to people with cognitive deficits. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
Keywords:
Alzheimer's disease
Functional performance representation
Cognitive modelling
Cognitive architecture
ACT-R
Activity of daily living
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