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A Hybrid Two-Stage Teaching-Learning-Based Optimization Algorithm for Feature Selection in Bioinformatics

delete2023-05-01
delete19
PRE
AI
康
康艳 (Yan Kang)
H
Haining Wang
B
Bin Pu *
T
Tao Liu
陈建国 cover
陈建国 (Chen, Jianguo)
P
Philip S. Yu
DOI:10.1109/TCBB.2022.3215129delete
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Abstract

Abstract

En 中文
The curse of dimensionality brings new challenges to the feature selection (FS) problem, especially in bioinformatics filed. In this paper, we propose a hybrid Two-Stage Teaching-Learning-Based Optimization (TS-TLBO) algorithm to improve the performance of bioinformatics data classification. In the selection reduction stage, potentially informative features, as well as noisy features, are selected to effectively reduce the search space. In the following comparative self-learning stage, the teacher and the worst student with self-learning evolve together based on the duality of the FS problems to enhance the exploitation capabilities. In addition, an opposition-based learning strategy is utilized to generate initial solutions to rapidly improve the quality of the solutions. We further develop a self-adaptive mutation mechanism to improve the search performance by dynamically adjusting the mutation rate according to the teacher's convergence ability. Moreover, we integrate a differential evolutionary method with TLBO to boost the exploration ability of our algorithm. We conduct comparative experiments on 31 public data sets with different data dimensions, including 7 bioinformatics datasets, and evaluate our TS-TLBO algorithm compared with 11 related methods. The experimental results show that the TS-TLBO algorithm obtains a good feature subset with better classification performance, and indicates its generality to the FS problems.
Keywords:
Feature selection
teaching-learning-based optimization
data classification
hybrid search

Journal

I
IEEE-ACM Transactions on Computational Biology and Bioinformatics
IF:
3.4
Papers:
3.3K
Citations:
6.4K

Organization

Y
Yunnan University
Scholars:
1.6W
Papers: 9.9K
Citations: 13
H
hunan university
Scholars:
4.5W
Papers: 3.3W
Citations: 70
University of Illinois System cover
University of Illinois System
Scholars:
6.9W
Papers: 6.2W
Citations: 644
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