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Abstract
En 中文
The past quarter century has witnessed rapid developments of fluorescence microscopy techniques that enable structural and functional imaging of biological specimens at unprecedented depth and resolution. The performance of these methods in multicellular organisms, however, is degraded by sample-induced optical aberrations. Here I I I review recent work on incorporating adaptive optics, a technology originally applied in astronomical telescopes to combat atmospheric aberrations, to improve image quality of fluorescence microscopy for biological imaging.
Keywords:
STRUCTURED ILLUMINATION MICROSCOPY
EMISSION DEPLETION MICROSCOPY
SINGLE-MOLECULE LOCALIZATION
SPECIMEN-INDUCED ABERRATIONS
WAVE-FRONT CORRECTION
PROTEIN GUIDE-STARS
MULTIPHOTON MICROSCOPY
CONFOCAL MICROSCOPY
2-PHOTON MICROSCOPY
IN-VIVO
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