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An Improved Muti-Task Learning Algorithm for Analyzing Cancer Survival Data

delete2021-03-01
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古万荣 (Wanrong Gu)
Z
Ziye Zhang *
X
Xianfen Xie
Y
Yichen He
DOI:10.1109/TCBB.2019.2920770delete
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Abstract

Abstract

En 中文
Survival analysis is a popular branch of statistics. At present, many algorithms (like traditional multi-tasking learning model) cannot be applied well in practice because of censored data. Although using some model (like parametric regression model) can avoid it, they need strict assumptions. This undermines the very nature of things, which is very detrimental to the study of practical problems. The method proposed in this paper can apply well to the censored data, but does not need to make any additional assumptions about the original problem. It can be said that it breaks through the above two kinds of major limitations. The algorithm is a kind of inductive transfer learning method, which can fully obtain the information in the censored data, using domain-specific information implicit in each feature to enhance the generalization capability of the model. We also used two common performance metrics as criteria to judge the predictive performance differences between the models in this article and those of other mainstream models. The results show that the model proposed in this paper is 10 similar to 15 percent higher than other mainstream models, which proves that our multi-task learning model has a great advantage in the survival analysis of cancer genes.
Keywords:
Data models
Analytical models
Cancer
Prediction algorithms
Predictive models
Task analysis
Indexes
Cancer genes
multi tasking
ADMM
survival analysis
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Journal

I
IEEE-ACM Transactions on Computational Biology and Bioinformatics
IF:
3.4
Papers:
3.3K
Citations:
6.4K

Organization

S
South China Agricultural University
Scholars:
3.1W
Papers: 1.5W
Citations: 2.6W
J
jinan university
Scholars:
4.3W
Papers: 2.6W
Citations: 38
S
south china university of technology
Scholars:
6.7W
Papers: 5.1W
Citations: 85
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