Bile salt hydrolase: A key target for developing high-performance probiotics

Shishen Liu

doi:10.1016/j.tifs.2025.105383

Bile salt hydrolase: A key target for developing high-performance probiotics

2025-10-13

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DOI：10.1016/j.tifs.2025.105383

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• Elucidates structural characteristics of bile salt hydrolase (BSH) in lactic acid bacteria (LAB) and their role in functional mechanisms. • Identifies key factors influencing BSH activity and summarizes innovative regulation strategies. • Highlights multifaceted roles of BSH-active LAB in human health. • Reviews potential applications of BSH in health products, food, animal performance, and bioenergy. • Evaluates current limitations and outlines future research directions for BSH-active probiotics.

Bile salt hydrolase: A key target for developing high-performance probiotics

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