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Cellular deconvolution with continuous transitions
DOI:10.1038/s43588-023-00489-0.png)
Abstract
En 中文
A recent work introduces a cellular deconvolution method, MeDuSA, of estimating cell-state abundance along a one-dimensional trajectory from bulk RNA-seq data with fine resolution and high accuracy, enabling the characterization of cell-state transition in various biological processes.
Journal
IF:
18.3
Papers:
3.1K
Citations:
4.0K
Organization
Cited Papers
The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
NATURE BIOTECHNOLOGY
IF41.7
Mixed model-based deconvolution of cell-state abundances (MeDuSA) along a one-dimensional trajectory
A benchmark for RNA-seq deconvolution analysis under dynamic testing environments
GENOME BIOLOGY
IF9.4
Determining cell type abundance and expression from bulk tissues with digital cytometry
NATURE BIOTECHNOLOGY
IF41.7
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