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Chitosan-modified liposomes for improved oral delivery of dihydromyricetin: synergistic stabilization, pH-responsive release, and markedly enhanced bioaccessibility

delete2026-07-30
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OA
AI
H
Hui Teng
M
Minyi Yan
C
Chong Chen *
C
Chao Ai
H
Huangjuan Huo
L
Lei Chen
DOI：10.1016/j.fochx.2026.104259delete
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Abstract

Abstract

En 中文
• Chitosan-modified DMY liposomes showed higher encapsulation efficiency. • Chitosan boosts DMY's antioxidant activity through synergistic interactions. • Chitosan-modified liposomes presented improved stability and sustained release. • Chitosan-modified liposomes remained intact in simulated gastrointestinal digestion. • Chitosan-modified liposomes achieved 2.67× DMY bioaccessibility vs free form (9.73%).
Keywords:
Dihydromyricetin
Chitosan
Liposomes
In vitro release
Gastrointestinal digestion

Journal

Food Chemistry-X cover
Food Chemistry-X
IF:
8.2
Papers:
2.7K
Citations:
9.8K

Organization

No organization information available
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