COPIng with senescence

Stella Victorelli

doi:10.1038/s41556-023-01276-9

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COPIng with senescence

2023-11-27

PRE

Stella Victorelli

João F. Passos *

DOI：10.1038/s41556-023-01276-9

Original

Original request for help

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Abstract

En 中文

There is increasing interest in approaches that target and eliminate senescent cells. A study reports that the coatomer complex I (COPI) pathway is important for the survival of senescent cells, and suggests that targeting this pathway could hold therapeutic promise in the context of senescence-associated diseases.

Journal

Nature Cell Biology

IF:

19.1

Papers:

6.2K

Citations:

4.8W

Organization

mayo clinic

Scholars:

8.3W

Papers: 6.6W

Citations: 85

Cited Papers

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The structure of COPI vesicles and regulation of vesicle turnover

FEBS LETTERS

IF3

2022-12-30

OAAI

Taylor, Rebecca J. J.; Tagiltsev, Grigory; Briggs, John A. G.

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COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells

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IF19.1

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McHugh, Domhnall; Sun, Bin; Gutierrez-Munoz, Carmen; Hernandez-Gonzalez, Fernanda; Mellone, Massimiliano; Guiho, Romain; Duran, Imanol; Pombo, Joaquim; Pietrocola, Federico; Birch, Jodie; Kallemeijn, Wouter W.; Khadayate, Sanjay; Dharmalingam, Gopuraja; Vernia, Santiago; Tate, Edward W.; Martinez-Barbera, Juan Pedro; Withers, Dominic J.; Thomas, Gareth J.; Serrano, Manuel; Gil, Jesus

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Targeting N-myristoylation for therapy of B-cell lymphomas

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IF15.7

2020-10-22

OAAI

Beauchamp, Erwan; Yap, Megan C.; Iyer, Aishwarya; Perinpanayagam, Maneka A.; Gamma, Jay M.; Vincent, Krista M.; Lakshmanan, Manikandan; Raju, Anandhkumar; Tergaonkar, Vinay; Tan, Soo Yong; Lim, Soon Thye; Dong, Wei-Feng; Postovit, Lynne M.; Read, Kevin D.; Gray, David W.; Wyatt, Paul G.; Mackey, John R.; Berthiaume, Luc G.

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The COPI system: Molecular mechanisms and function

FEBS LETTERS

IF3

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267

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N-myristoylation: from cell biology to translational medicine

ACTA PHARMACOLOGICA SINICA

IF8.4

2020-03-18

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NATURE REVIEWS CLINICAL ONCOLOGY

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Peritoneal drainage as primary management of perforated NEC in the very low birth weight infant

Journal of Pediatric Surgery

IF0

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