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Acta Pharmacologica Sinica cover

Acta Pharmacologica Sinica

IF8.4
Papers4362
Citations18195
Journal Papers 9817
Publication Date
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Hyper-O-GlcNAcylation destabilizes ARC to unleash NLRP3-mediated pyroptosis in diabetic cardiomyopathy
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-12
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deleteLin Ye; Meng-yang Li; Xiang Ao; Dan-dan Xiao; Yu Wang; Pei-yan Wang; Qi Li; Wei Ding; Jian-xun Wang
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Protein–protein interaction-mediated signaling networks in ischemic stroke: from molecular mechanisms to therapeutic strategies
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-10
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deleteYi-yue Zhang; Xing-yu Long; Kai-jia Wang; Jing Tian; Jin-yun Xu; Xiu-ju Luo
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Emerging roles of mitophagy in liver fibrosis: Implications for therapy
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-10
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deleteZi-yang Zhao; Shu-na Tong; Run-hao Lin; Shi-yi Feng; Ying Yang; Xing-juan Shi
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Gut microbiota modulation of gastrointestinal cancers: from dysbiosis signatures to therapeutic interventions
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-06
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deleteXin-yu Li; Zuo-quan Xie; Mei-yu Geng
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Smoothened signaling in microglia: canonical or not, and does it promote or limit inflammation?
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-05
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deleteAdil El Mesaoudi; Dong Won Kim; Elisabeth Traiffort
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Secreted chimeric proteins as a strategy to correct SOX17 deficiency and attenuate the malignant phenotype of cholangiocarcinoma cells: a proof-of-concept study
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-04
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deleteAna Peleteiro-Vigil; Sara Ortiz-Rivero; Yanira Izquierdo-Mateo; Laura Sanchez-Vicente; Ester González-Sánchez; Javier Vaquero; Juan Carlos Arevalo; Oscar Briz; Maria J. Monte; Jose J. G. Marin; Elisa Herraez
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miR-203 improves pressure overload-induced heart failure by targeting the IGFBP5/PI3K/AKT axis
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-04
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deletePing-ping Tang; Run Xu; Song Wang; Wei-yi Zhang; Xin-xin Dong; Li-na Yao; Ling-yi Kong; Chang Mao; Yu-dong Bao; Hui-qian Tang; Dian-ya Sun; Ning Wang; Xin Liu; Yong Zhang
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Targeting FOSL1-KCa3.1 inhibits ferroptosis and cartilage destruction by suppressing mitochondrial hyperfusion
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-04
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deleteRen-peng Zhou; Shu-fang Li; Ke Wang; Xing-yu Liu; Hao-yu Liu; Peng Yu; Yu-fan Zhang; Wei-rong Hu; Yu-cai Xu; Jie Ding; Cheng Sun; Ying-jie Zhao; Feng Yao; Wei Wei; Chao Lu; Wei Hu
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Beyond conventional therapies: the evolution of targeted agents and immunotherapies in triple-negative breast cancer
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-04
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deleteHui-fang Cheng; Yan-mei Chen; Pei-yan Liu; Xin Jin; Yi Qu; Bo Liu; Ai-zhuo Li
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STK40 inhibits profibrotic Arg1+ macrophage differentiation and renal fibrosis by regulating poly-ubiquitination of STAT3
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-04
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deleteJun Ni; Jia Li; Si-ying Sun; Jia-min Liu; Zhen-yan Jiang; Yue-xiao Tao; Hui-zi Wang; Ge-ge He; Seyedeh Sara Ahmadi Nishaboori; Xin Li; Xi-yu Liu; Xue-zhu Li; Zhe Ji; Hui-yao Lan; Dan-dan Zhang; Xue-feng Wu
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Ginkgo biloba L. in preventing cardiovascular disease: pharmacological effects, mechanism of action, and therapeutic potential
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-04
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deleteMin Tao; Wei-le Ye; Jiao-jiao Wang; Zhi-ping Liu
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PGK1-driven histone lactylation fuels MDSC-driven immune evasion and tumor progression in triple-negative breast cancer
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-04
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deleteYong-peng Wang; Wen-zhen Dang; Zhen-dan Liu; Bing Li; Huan Xiong; Hudagula Bai; Xiao Li; Shuo Wu; Cheng Luo; Wei-lie Xiao; Yuan-yuan Zhang
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Enhanced substance P-NK1R signaling in the parabrachial–parasubthalamic pathway promotes hyperalgesia and affective aversion in neuropathic pain
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-04
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deleteFang Rao; Ming-xin Tang; Hang Yang; Tian-hai Wang; Chun-yi Zhou; Cheng Xiao
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Cardiomyocyte OTUD7b drives diabetic cardiomyopathy via deubiquitinating and stabilizing TAK1
deleteActa Pharmacologica Sinica
IF8.4
delete2026-08-03
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deleteXue Han; Guo-xuan Liu; Jia-ning Zheng; Ming-yang He; Li Zhuang; Jia-jia Zhang; Jie Tong; Zhu-qi Huang; Yu-rou Wu; Tong-qing Zhou; Ju-lin Min; Ze-ping Zhang; Ning Zhu; Qiao-juan Shi; Wen-bing Jiang; Hua-zhong Ying; Guang Liang
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Macrophage FOLR2 drives liver fibrosis via intercellular engagement of TGFβRII
deleteActa Pharmacologica Sinica
IF8.4
delete2026-07-30
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deleteMan-man Yuan; Bing-feng Zheng; Jing-lin Wang; Shuai-qi Xu; Sheng-lan Wang; Yang Tan; Yong Feng; Xian-chi Dong; Qi-hua Zhu; Jie Yan; Qiang Xu; Xing-xin Wu
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Pulsatile FXR activation: Timing bile acid-targeted therapy to physiology
deleteActa Pharmacologica Sinica
IF8.4
delete2026-07-29
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deleteTing-ying Jiao; Yang-tai Li; Frank J. Gonzalez; Cen Xie
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SERCA2 gatekeeper role in aortic autophagy: targeting the Ca2+-mTOR axis to prevent aortic dissection
deleteActa Pharmacologica Sinica
IF8.4
delete2026-07-27
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PREAI
deleteLang-tao Wang; Xun Chen; Jia-rou Song; Jun-cai Liu; Sai Wang; Zhen Yang; Rui Su; Jiang-jie Long; Yu Peng; Ping-ping Hu; Gang Liu; Si-qi Li; Hao Chen; Xiao-yong Tong
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Targeting JOSD2 degrades β-catenin to suppress colorectal cancer metastasis by disrupting RAS/ERK/β-catenin axis
deleteActa Pharmacologica Sinica
IF8.4
delete2026-07-22
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deleteYue Liu; Shu-yu Yang; Wen-han Zhang; Yan-ting Liang; Jun-wei Fu; Jing-yu Dai; Rui-lin Wu; Chu-run Zheng; Hao-tong Wang; Yong-hao Li; Run-qiu Guo; Chen-ming Zeng; Xiang-yu Xu; Zheng-bo Song; Chun-wei Xu; Ji Cao; Qiao-jun He; Hong Zhu; Tao Yuan; Bo Yang
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KCNE2 upregulation improves cardiac function by inhibiting Smurf1-mediated SERCA2a degradation in diabetic cardiomyopathy in mice
deleteActa Pharmacologica Sinica
IF8.4
delete2026-07-22
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deleteMing Song; Kai-ping Gao; Jie Yang; Yu-qi Tu; Yi-xin Zhu-Ge; Wan-wen Cheng; Gang Wang; Ying Li; Wen-juan Liu; Jie Liu
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ATF3/SOX11-regulated FST activates IGF1R–ERK/AKT–Sp1 signaling to sustain trigeminal neuropathic pain
deleteActa Pharmacologica Sinica
IF8.4
delete2026-07-21
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deleteYue-juan Ling; Bing Zhu; Zuo-hao Yao; Ling-jie Ma; Lin-peng Zhu; Jing Zhang; Fei-fei Xu; Hao Wu; Lu-lu Ji; Yong-jing Gao
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