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Deciphering S-nitrosylation-regulated metabolic networks in postmortem beef based on label-free modificomics: Identification of ferroptosis as a novel quality-related pathway
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DOI：10.1016/j.meatsci.2026.110191.png)
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Abstract
En 中文
• S-nitrosylation improved beef pH and WHC but decreased tenderness. • Label-free modificomics first identified 125% more S-nitrosylated proteins in beef. • S-nitrosylation modulates multiple metabolic processes, with ferroptosis as a novel pathway. • ACSL, CP, and TF are candidate biomarkers of S-nitrosylation-regulated ferroptosis. • Correlation analysis supports SNO-ferroptosis role in beef quality regulation.
Keywords:
S-nitrosylation
Metabolic pathways
Beef quality
Label-free modificomics
Ferroptosis
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2.8W
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