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Decoding 3D cell morphology with interpretable point cloud models

delete2025-07-03
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Siewert Hugelier *
DOI:10.1038/s41592-025-02752-wdelete
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Abstract

Abstract

En 中文
The morphology of fragmented cellular structures can be captured by converting microscopy images to 3D point clouds and analyzing them with rotation-invariant deep-learning models. These compact models represent a powerful alternative to conventional pixel-based analysis pipelines because they achieve high reconstruction and classification accuracies while remaining fast and biologically interpretable.

Journal

Nature Methods cover
Nature Methods
IF:
32.1
Papers:
7.2K
Citations:
12.7W

Organization

P
Perelman School of Medicine
Scholars:
666
Papers: 246
Citations: 1