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Decoding bioprocesses with transcriptomics: Current status and future potential
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DOI：10.1016/j.biotechadv.2025.108736.png)
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Abstract
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• Status quo of high throughput transcriptomics applied in bioprocess engineering. • Scopes of the reviewed studies: strain/cell line characterization, culture/media conditions, process operation modes and parameters as well as scale-up/down. • RNA-seq as gold-standard transcriptomic workflow. • Single-cell RNA-seq and Record-Seq to unravel population heterogeneities and cellular autobiographies.
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