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Deep learning-based single-shot structured illumination microscopy

delete2022-08-01
delete24
PRE
AI
Q
Qinnan Zhang
J
Jiawei Chen
J
Jiaosheng Li
E
En Bo
H
He-ming Jiang
X
Xiaoxu Lü
L
Liyun Zhong
J
Jindong Tian *
DOI:10.1016/j.optlaseng.2022.107066delete
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Abstract

Abstract

En 中文
We report a deep learning-based structured illumination microscopy (SIM) method, which can reconstruct a super-resolution (SR) image using only one frame structured illumination image. Generative adversative networks (GANs) and deformation of U-Net (DU-Net) are employed to perform the task. GANs are trained to generate other structured illumination images by feeding a single structured illumination image, and DU-Net is trained to reconstruct the super-resolution image. The results of experiments and simulations demonstrate that the SR image could be reconstructed from one frame structured illumination image. Importantly, it can greatly reduce phototoxicity and photobleaching.
Keywords:
Structured illumination microscopy
Super-resolution
Deep learning

Journal

Optics and Lasers in Engineering cover
Optics and Lasers in Engineering
IF:
3.7
Papers:
7.3K
Citations:
1.7W

Organization

S
south china normal university
Scholars:
2.0W
Papers: 1.3W
Citations: 13
S
shenzhen university
Scholars:
4.6W
Papers: 3.4W
Citations: 72
B
beijing genomics institute (bgi)
Scholars:
5.2K
Papers: 2.1K
Citations: 7
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Cited Papers

Cited Papers

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Deep-STORM: super-resolution single-molecule microscopy by deep learning
errOPTICA
IF8.5
err2018-04-12
err472
errOAAI
errNehme, Elias; Weiss, Lucien E.; Michaeli, Tomer; Shechtman, Yoav
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Deep learning massively accelerates super-resolution localization microscopy
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errOuyang, Wei; Aristov, Andrey; Lelek, Mickael; Hao, Xian; Zimmer, Christophe
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Deep learning approach to Fourier ptychographic microscopy
err2018-09-26
err235
errOAAI
errThanh Nguyen; Xue, Yujia; Li, Yunzhe; Tian, Lei; Nehmetallah, George
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researcher View more