Degradation of Ethyl Carbamate by Lichtheimia ramosa EC-2 from Baijiu Daqu: Optimization, Metabolites, and Key Enzymes

Haixiong Qin

doi:10.1016/j.fm.2026.105206

Degradation of Ethyl Carbamate by Lichtheimia ramosa EC-2 from Baijiu Daqu: Optimization, Metabolites, and Key Enzymes

2026-06-19

0

PRE

AI

H

Haixiong Qin

X

Xinpeng Guo

J

Jia Zheng

B

Bowen Xu

Y

Ying Lei

X

Xinyi Huang

Z

Zhengmin Xie

D

Dong Zhao

J

Jiayuan Zhao *

DOI：10.1016/j.fm.2026.105206

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• Lichtheimia ramosa EC-2 degraded ethyl carbamate by 42.29% within 7 days. • Strain EC-2 tolerated high ethyl carbamate levels and up to 15% (v/v) ethanol. • Multi-omics suggested a shift of carbon flux toward acetyl-CoA-related metabolism during EC utilization. • EC-2 altered community functions related to carbon/nitrogen metabolism and reduced arginine-related precursor pathways. • A novel amidase (TR3551) hydrolyzed EC and remained active under elevated temperature and ethanol.

Degradation of Ethyl Carbamate by Lichtheimia ramosa EC-2 from Baijiu Daqu: Optimization, Metabolites, and Key Enzymes

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